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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MEILQHVIDY ILDLQIALDS HPTIVSLHHQ RPGQNQASRT PLTTLNTDIS ILSLQASEFP SELMSNDSKA LCG
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 97%.
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of a number of cell types including natural killer cell, erythroid precursors, as well as, CD8+ and CD4+ T-cell. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins, and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHb26; Class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID-2; Inhibitor of differentiation 2; Inhibitor of DNA binding 2; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297
基因别名: BHLHB26; ID2
Entrez Gene ID: (Human) 3398