FIGURE: 1 / 1
Peptide sequence: LIEIERCEPV RSKLEEVQRK LGFALSDISV VSNYSSEWEL DPVKDVLILS
Sequence homology: Human: 100%
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-βs, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
Protein Aliases: Interferon-induced protein 44; interferon-induced, hepatitis C-associated microtubular aggregate protein (44kD); Microtubule-associated protein 44; p44; TBC/LysM-associated domain containing 5
Gene Aliases: IFI44; MTAP44; p44; TLDC5
UniProt ID: (Human) Q8TCB0
Entrez Gene ID: (Human) 10561