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Abnova
IFIH1 Monoclonal Antibody (3F6)
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产品信息
H00064135-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3F6
抗原
IFIH1 (NP_071451.2, 928 a.a. approximately 1023 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.49 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: HVNMTPEFKE LYIVRENKAL QKKCADYQIN GEIICKCGQA WGTMMVHKGL DLPCLKIRNF VVVFKNNSTK KQYKKWVELP ITFPNLDYSE CCLFSD
靶标信息
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CADM-140 autoantigen; clinically amyopathic dermatomyositis autoantigen 140 kDa; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; helicard; helicase with 2 CARD domains; melanoma differentiation-associated gene 5; melanoma differentiation-associated protein 5; MGC133047; murabutide down-regulated protein; RIG-I-like receptor 2; RNA helicase-DEAD box protein 116; unnamed protein product
基因别名: AGS7; Hlcd; IDDM19; IMD95; MDA-5; MDA5; RLR-2; SGMRT1
UniProt ID: (Human) Q9BYX4
Entrez Gene ID: (Human) 64135
DNA binding
RNA binding
RNA helicase activity
double-stranded RNA binding
single-stranded RNA binding
protein binding
ATP binding
zinc ion binding
hydrolase activity
ATPase activity
protein domain specific binding
pattern recognition receptor activity
identical protein binding
ribonucleoprotein complex binding
cytoplasmic pattern recognition receptor signaling pathway
signal transduction
detection of virus
response to virus
protein sumoylation
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of type III interferon production
MDA-5 signaling pathway
negative regulation of viral genome replication
innate immune response
protein oligomerization
defense response to virus
positive regulation of response to cytokine stimulus
cellular response to exogenous dsRNA
cellular response to virus
antiviral innate immune response
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