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IFIT1 Polyclonal Antibody

查看其他5个IFIT1抗体

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说明书
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问题与答案
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说明书
实验方案
问题与答案
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说明书
实验方案
问题与答案
技术支持
IFIT1 Polyclonal Antibody

产品信息

600-401-BT2

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1-2 µg/mL
-

免疫组化（石蜡） (IHC (P))

5 µg/mL
-

免疫细胞化学 (ICC/IF)

20 µg/mL
-

酶联免疫吸附实验 (ELISA)

1:10,000-1:20,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Anti-IFIT1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human IFIT1.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: GARG-16; glucocorticoid-attenuated response gene 16 product; Glucocorticoid-attenuated response gene 16 protein; IFI-56K; IFIT-1; interferon, alpha-inducible protein (MW 56kD); Interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1; interferon-induced protein with tetratricopeptide repeats 1-like protein; interferon-inducible mRNA 561

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基因别名: C56; G10P1; Garg16; IFI-56; IFI-56K; IFI56; IFIT-1; IFIT1; IFNAI1; ISG56; P56; RNM561

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UniProt ID: (Human) P09914, (Mouse) Q64282

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Entrez Gene ID: (Human) 3434, (Mouse) 15957, (Rat) 56824

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