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Proteintech
IFITM2/3 Monoclonal Antibody (2E8D12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
66081-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2E8D12
抗原
IFITM2/3 Fusion Protein Ag17863 (1-133 aa encoded by BC070243)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.85 mg/mL
规格
127.5 µg
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody recognizes both IFITM2 and IFITM3.
Immunogen sequence: MNHTVQTFF SPVNSGQPPN YEMLKEEHEV AVLGAPHNPA PPTSTVIHIR SETSVPDHVV WSLFNTLFMN PCCLGFIAFA YSVKSRDRKM VGDVTGAQAY ASTAKCLNIW ALILGILMTI LLIVIPVLIF QAYG (1-133 aa encoded by BC070243)
靶标信息
IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1-8D; 1-8U; dispanin subfamily A member 2b; dispanin subfamily A member 2c; IFITM2; ifm2; interferon-inducible protein 1-8D; interferon-inducible protein 1-8U; unnamed protein product
基因别名: 1-8D; 1-8U; DSPA2b; DSPA2c; IP15
UniProt ID: (Human) Q01629, (Human) Q01628
Entrez Gene ID: (Human) 10581, (Human) 10410
immune response
response to virus
response to interferon-gamma
response to interferon-alpha
response to interferon-beta
cellular response to interferon-beta
negative regulation of viral genome replication
negative regulation of viral entry into host cell
defense response to virus
type I interferon signaling pathway
negative regulation of viral transcription
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