Leinco Technologies

IFN alpha Monoclonal Antibody (TIF-3C5), Functional Grade, In Vivo PLATINUM™

Name: IFN alpha Monoclonal Antibody (TIF-3C5), Functional Grade, In Vivo PLATINUM\u2122
Brand: Leinco Technologies
SKU: T701-1MG

查看其他34个IFN alpha抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

T701-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

中和实验 (Neu)

Assay-dependent

功能检测 (Functional)

Assay-dependent

抑制试剂 (Inhibition)

Assay-dependent

产品规格

种属反应

Mouse

宿主/亚型

Armenian hamster / IgG1

分类

Monoclonal

类型

Antibody

克隆号

TIF-3C5

抗原

Recombinant murine IFN alpha 5

偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Clone TIF-3C5 recognizes an epitope on mouse IFN-alpha (subtypes IFN-alpha A, -1, -4, -5, -11, and -13) and does not bind murine IFN-gamma or IFN-Beta.

Endotoxin Level: <0.5 EU/mg as determined by the LAL method. Purity: >95% by SDS Page; ≥98% monomer by analytical SEC.

Product Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.

Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80 C. Avoid Repeated Freeze Thaw Cycles.

This antibody has been tested in the following applications: Western Blotting, Neutralization, Functional Assay, Blocking.

靶标信息

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ifa; IFN alpha 1/13; IFN alpha 1b; IFN α; IFN-alpha-1; IFN-alpha-2; IFNAalphaIFN-alpha-1/13; IFNalpha; IFNα; Interferon alpha 13 (IFNA13); interferon alpha 15; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha leukocyte (IFL); Interferon alpha-1; Interferon alpha-1/13 (IFN-alpha-1/13); interferon alpha-2; Interferon alpha-D (IFN alphaD); Interferon alpha1 (IFNA1); MGC138207; MGC138505; MGC138507; novel interferon alpha (Ifna) family member

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基因别名: Gm12597; Ifa1; Ifa2; Ifna1; Ifnaa; MuIFN-alpha-A; OTTMUSG00000007655

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UniProt ID: (Mouse) P01572

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Entrez Gene ID: (Mouse) 15962, (Mouse) 242517, (Mouse) 15965

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功能

cytokine activity cytokine receptor binding type I interferon receptor binding interferon superfamily

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