Leinco Technologies

IFN beta Monoclonal Antibody (HDb-4A7), Functional Grade, In Vivo GOLD™

Name: IFN beta Monoclonal Antibody (HDb-4A7), Functional Grade, In Vivo GOLD\u2122
Brand: Leinco Technologies
SKU: I-1182-1MG

查看其他24个IFN beta抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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IFN beta Antibody (I-1182-1MG) in WB

Western Blot analysis of IFN beta in reduced recombinant mouse IFN-beta protein using IFN beta Monoclonal Antibody (Product # I-1182-1MG).

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产品信息

I-1182-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

中和实验 (Neu)

Assay-dependent

功能检测 (Functional)

Assay-dependent

抑制试剂 (Inhibition)

Assay-dependent

产品规格

种属反应

Mouse

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

HDb-4A7

抗原

Plasmid DNA encoding murine IFNb

偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Mouse Anti-Mouse Interferon-beta (IFN-Beta) (Clone HDBeta-4A7) recognizes an epitope on Mouse IFN-Beta and binds specifically to murine IFN-Beta and does not bind murine IFN-gamma or several different IFN-alpha species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms. This antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Endotoxin Level: ≤ 1.0 EU/mg as determined by the LAL method. Purity: >95% by SDS Page; ≥95% monomer by analytical SEC.

Product Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80 C. Avoid Repeated Freeze Thaw Cycles.

This antibody has been tested in the following applications: Western Blotting, Neutralization, Functional Assay, Blocking.

靶标信息

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。