Product References
Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.
Frontiers in immunology
Wang A,Yang M,Liang R,Zhu F,Zhu F,Liu X,Han Y,Lin R,Wang X,Li D,Li H,Yuan X,Zhao H,Li B
17-7319 was used in Flow cytometry/Cell sorting to investigate how mouse double minute 2 homolog effects the function of regulatory T cells.
Mon Apr 05 00:00:00 EDT 2021
A Method of Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood.
Frontiers in immunology
Market M,Tennakoon G,Ng J,Scaffidi M,de Souza CT,Kennedy MA,Auer RC
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Mon Mar 29 00:00:00 EDT 2021
Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells.
Oncoimmunology
Seebauer CT,Brunner S,Glockzin G,Piso P,Ruemmele P,Schlitt HJ,Geissler EK,Fichtner-Feigl S,Kesselring R
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
17-7319 was used in Flow cytometry/Cell sorting to study DEK-targeting aptamer in EMT-mediated airway remodeling in asthma.
Tue Dec 01 00:00:00 EST 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
17-7319 was used in Flow cytometry/Cell sorting to study DEK-targeting aptamer in EMT-mediated airway remodeling in asthma.
Tue Dec 01 00:00:00 EST 2020
Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes.
Journal of extracellular vesicles
Salimu J,Webber J,Gurney M,Al-Taei S,Clayton A,Tabi Z
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap.
Nature protocols
Bounab Y,Eyer K,Dixneuf S,Rybczynska M,Chauvel C,Mistretta M,Tran T,Aymerich N,Chenon G,Llitjos JF,Venet F,Monneret G,Gillespie IA,Cortez P,Moucadel V,Pachot A,Troesch A,Leissner P,Textoris J,Bibette J,Guyard C,Baudry J,Griffiths AD,Védrine C
17-7319-41 was used in Flow Cytometry to develop a microfluidic platform, DropMap, for the phenotyping of different immune cell types.
Tue Sep 01 00:00:00 EDT 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Thu Aug 20 00:00:00 EDT 2020
TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease.
Oncology reports
Zhu F,Qiu T,Zhu S,Zhao K,Chen C,Qiao J,Pan B,Yan Z,Chen W,Liu Q,Wu Q,Cao J,Sang W,Zeng L,Sun H,Li Z,Xu K
17-7319 was used in Flow cytometry/Cell sorting to deepen the understanding of the pathogenesis of acute graft-versus-host disease (GVHD) and provide novel approaches for controlling acute GVHD.
Wed Jul 01 00:00:00 EDT 2020
Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer.
Cell reports. Medicine
Li S,Simoni Y,Becht E,Loh CY,Li N,Lachance D,Koo SL,Lim TP,Tan EKW,Mathew R,Nguyen A,Golovato J,Berkson JD,Prlic M,Lee B,Minot SS,Nagarajan N,Dey N,Tan DSW,Tan IB,Newell EW
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines.
Nature communications
Cano-Gamez E,Soskic B,Roumeliotis TI,So E,Smyth DJ,Baldrighi M,Willé D,Nakic N,Esparza-Gordillo J,Larminie CGC,Bronson PG,Tough DF,Rowan WC,Choudhary JS,Trynka G
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Tue Apr 14 00:00:00 EDT 2020
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Nature communications
Qin G,Wang X,Ye S,Li Y,Chen M,Wang S,Qin T,Zhang C,Li Y,Long Q,Hu H,Shi D,Li J,Zhang K,Zhai Q,Tang Y,Kang T,Lan P,Xie F,Lu J,Deng W
17-7319-41 was used in Flow Cytometry to verify that triple-negative breast cancer (TNBC) has higher PD-L1 expression than other subtypes.
Fri Apr 03 00:00:00 EDT 2020
Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma.
Molecular therapy oncolytics
Zhao L,Liu Y,Zhao F,Jin Y,Feng J,Geng R,Sun J,Kang L,Yu L,Wei Y
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues.
Nature immunology
Cella M,Gamini R,Sécca C,Collins PL,Zhao S,Peng V,Robinette ML,Schettini J,Zaitsev K,Gordon W,Bando JK,Yomogida K,Cortez V,Fronick C,Fulton R,Lin LL,Gilfillan S,Flavell RA,Shan L,Artyomov MN,Bowman M,Oltz EM,Jelinsky SA,Colonna M
17-7319 was used in Flow cytometry/Cell sorting to demonstrate that innate lymphoid cells (ILCs) undergo conversion from ILC3s into ILC1-like cells in human tissues in vivo, requiring tissue factors and Aiolos in the process.
Thu Aug 01 00:00:00 EDT 2019
Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway.
Nature communications
Tang-Huau TL,Gueguen P,Goudot C,Durand M,Bohec M,Baulande S,Pasquier B,Amigorena S,Segura E
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Mon Jul 02 00:00:00 EDT 2018
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
RKIP mediates autoimmune inflammation by positively regulating IL-17R signaling.
EMBO reports
Lin W,Wang N,Zhou K,Su F,Jiang Y,Shou J,Liu H,Ma C,Qian Y,Wang K,Wang X
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.
Nature communications
Chen D,Xie J,Fiskesund R,Dong W,Liang X,Lv J,Jin X,Liu J,Mo S,Zhang T,Cheng F,Zhou Y,Zhang H,Tang K,Ma J,Liu Y,Huang B
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Wed Feb 28 00:00:00 EST 2018
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
NKG2C(+)CD57(+) Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8(+) T Cell Evolution towards Senescence.
Journal of immunology research
Heath J,Newhook N,Comeau E,Gallant M,Fudge N,Grant M
17-7319 was used in Flow cytometry/Cell sorting to explore the relationship between NKG2C(+)CD57(+) natural killer cells and the adaptive immune response to human cytomegalovirus.
Thu Mar 16 00:00:00 EDT 2017
Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens.
Oncotarget
Pathangey LB,McCurry DB,Gendler SJ,Dominguez AL,Gorman JE,Pathangey G,Mihalik LA,Dang Y,Disis ML,Cohen PA
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2017
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
PloS one
Singh S,Vedi S,Samrat SK,Li W,Kumar R,Agrawal B
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly.
PLoS neglected tropical diseases
Romano A,Hou X,Sertorio M,Dessein H,Cabantous S,Oliveira P,Li J,Oyegue S,Arnaud V,Luo X,Daujat-Chavanieu M,Chavanieu M,Mariani O,Sastre X,Dombey AM,He H,Li Y,Dessein A
17-7319 was used in Flow cytometry/Cell sorting to investigate whether FOXP3+ Tregs play a role in human schistosomiasis.
Fri Jan 01 00:00:00 EST 2016
A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes.
Nucleic acids research
Zhong F,Zhou N,Wu K,Guo Y,Tan W,Zhang H,Zhang X,Geng G,Pan T,Luo H,Zhang Y,Xu Z,Liu J,Liu B,Gao W,Liu C,Ren L,Li J,Zhou J,Zhang H
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Wed Dec 02 00:00:00 EST 2015
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
mAbs
Thaventhiran T,Alhumeed N,Yeang HX,Sethu S,Downey JS,Alghanem AF,Olayanju A,Smith EL,Cross MJ,Webb SD,Williams DP,Bristow A,Ball C,Stebbings R,Sathish JG
17-7319 was used in Flow cytometry/Cell sorting to understand the underlying molecular mechanisms of T-cell activation in response to TGN1412-like CD28 superagonist, showing that failure to upregulate the inhibitory PD-1 cell surface receptor is part of this mechanism.
Mon Aug 24 00:00:00 EDT 2015
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy.
Journal of immunology (Baltimore, Md. : 1950)
Rasouli J,Ciric B,Imitola J,Gonnella P,Hwang D,Mahajan K,Mari ER,Safavi F,Leist TP,Zhang GX,Rostami A
17-7319 was used in Flow cytometry/Cell sorting to characterise GM-CSF production by T cells of MS patients and to determine the effect of IFN-β therapy on its production.
Mon Jun 01 00:00:00 EDT 2015
Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus.
Journal of immunology (Baltimore, Md. : 1950)
Tsai CY,Liong KH,Gunalan MG,Li N,Lim DS,Fisher DA,MacAry PA,Leo YS,Wong SC,Puan KJ,Wong SB
17-7319 was used in Flow cytometry/Cell sorting to investigate the markers of cellular innate immunity against dengue virus, specifically how type I IFNs and IL-18 regulate activation, proliferation and degranulation of T cells against dendritic cells in human patients with dengue virus.
Wed Apr 15 00:00:00 EDT 2015
Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset.
The Journal of biological chemistry
Chauhan AK,Chen C,Moore TL,DiPaolo RJ
17-7319 was used in Flow cytometry/Cell sorting to describe for the first time a role for FcγRIIIa in CD4+ T-cell differentiation.
Fri Feb 20 00:00:00 EST 2015
Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset.
The Journal of biological chemistry
Chauhan AK,Chen C,Moore TL,DiPaolo RJ
17-7319 was used in Flow cytometry/Cell sorting to describe for the first time a role for FcγRIIIa in CD4+ T-cell differentiation.
Fri Feb 20 00:00:00 EST 2015
Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.
Immunology and cell biology
Zipperlen K,Gallant M,Stapleton S,Heath J,Barrett L,Grant M
17-7319 was used in Flow cytometry/Cell sorting to investigate how HLA/KIR genotypic combinations relate to the phenotype and function of CD8(+) T cells in individuals with HIV infection.
Thu Jan 01 00:00:00 EST 2015
The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus.
Journal of immunology (Baltimore, Md. : 1950)
Lim DS,Yawata N,Selva KJ,Li N,Tsai CY,Yeong LH,Liong KH,Ooi EE,Chong MK,Ng ML,Leo YS,Yawata M,Wong SB
17-7319 was used in Flow cytometry/Cell sorting to investigate the response of NK cells against dengue-infected cells, showing that a combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells is required.
Sat Nov 15 00:00:00 EST 2014
PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients.
British journal of cancer
Wu X,Zhang H,Xing Q,Cui J,Li J,Li Y,Tan Y,Wang S
17-7319 was used in Immunohistochemistry to evaluate the role of PD-1-PD-L1 pathway in CD8(+) T-cell functions in tumour-draining lymph nodes (TDLNs) and tumours of CRC patients.
Tue Sep 23 00:00:00 EDT 2014
PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients.
British journal of cancer
Wu X,Zhang H,Xing Q,Cui J,Li J,Li Y,Tan Y,Wang S
17-7319 was used in Immunohistochemistry to evaluate the role of PD-1-PD-L1 pathway in CD8(+) T-cell functions in tumour-draining lymph nodes (TDLNs) and tumours of CRC patients.
Tue Sep 23 00:00:00 EDT 2014
Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moon EK,Wang LC,Dolfi DV,Wilson CB,Ranganathan R,Sun J,Kapoor V,Scholler J,Puré E,Milone MC,June CH,Riley JL,Wherry EJ,Albelda SM
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Fri Aug 15 00:00:00 EDT 2014
Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma.
Oncotarget
Ye SB,Li ZL,Luo DH,Huang BJ,Chen YS,Zhang XS,Cui J,Zeng YX,Li J
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Wed Jul 30 00:00:00 EDT 2014
Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Ribeiro ST,Correia DV,Sousa AE,Silva-Santos B
17-7319 was used in Flow cytometry/Cell sorting to study how ex vivo-isolated γδ thymocytes produced negligible IFN-γ and lacked cytolytic activity against leukemia cells.
Sat Mar 01 00:00:00 EST 2014
BET bromodomain inhibition suppresses TH17-mediated pathology.
The Journal of experimental medicine
Mele DA,Salmeron A,Ghosh S,Huang HR,Bryant BM,Lora JM
17-7319 was used in Flow cytometry/Cell sorting to identify BET proteins as a fundamental link between chromatin signalling and T(H)17 biology.
Mon Oct 21 00:00:00 EDT 2013
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.
PLoS pathogens
Lindestam Arlehamn CS,Gerasimova A,Mele F,Henderson R,Swann J,Greenbaum JA,Kim Y,Sidney J,James EA,Taplitz R,McKinney DM,Kwok WW,Grey H,Sallusto F,Peters B,Sette A
17-7319 was used in Flow cytometry/Cell sorting to further define the immunological footprint of Mycobacterium tuberculosis CD4 T cell recognition.
Tue Jan 01 00:00:00 EST 2013
Brefeldin A, but not monensin, enables flow cytometric detection of interleukin-4 within peripheral T cells responding to ex vivo stimulation with Chlamydia trachomatis.
Journal of immunological methods
Vicetti Miguel RD,Maryak SA,Cherpes TL
17-7319 was used in Flow cytometry/Cell sorting to compare the ability of brefeldin A and monensin to concurrently trap 4 cytokines within peripheral blood mononuclear cells.
Wed Oct 31 00:00:00 EDT 2012
Peripherally circulating CD4⁺ FOXP3⁺ CXCR3⁺ T regulatory cells correlate with renal allograft function.
Scandinavian journal of immunology
Hoerning A,Köhler S,Jun C,Tebbe B,Fu J,Menke J,Wilde B,Dolff S,Feldkamp T,Briscoe DM,Kribben A,Hoyer PF,Witzke O
17-7319 was used in Flow cytometry/Cell sorting to investigate the relevance of trafficking receptors for Tregs after solid organ transplantation.
Sat Sep 01 00:00:00 EDT 2012
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using IFN gamma monoclonal antibody (Product # 17-7319-41) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
Science translational medicine
Rech AJ,Mick R,Martin S,Recio A,Aqui NA,Powell DJ,Colligon TA,Trosko JA,Leinbach LI,Pletcher CH,Tweed CK,DeMichele A,Fox KR,Domchek SM,Riley JL,Vonderheide RH
17-7319 was used in Flow cytometry/Cell sorting to conclude that CD25 blockade depletes and selectively reprograms T(regs) in concert with active immune therapy in cancer patients.
Wed May 16 00:00:00 EDT 2012
Role played by CD4+FOXP3+ regulatory T Cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers.
The Journal of infectious diseases
Li W,Tenner-Racz K,Racz P,Janowicz DM,Fortney KR,Katz BP,Spinola SM
17-7319 was used in Flow cytometry/Cell sorting to propose that the population of CD4(+)CD25(+)CD127(lo/-)FOXP3(+) T(reg) cells are expanded at H. ducreyi-infected sites and may supress the hosts immune response.
Tue Jun 15 00:00:00 EDT 2010
Human immunodeficiency virus type I-specific CD8+ T cell subset abnormalities in chronic infection persist through effective antiretroviral therapy.
BMC infectious diseases
Pohling J,Zipperlen K,Hollett NA,Gallant ME,Grant MD
17-7319 was used in Flow cytometry/Cell sorting to evaluate the magnitude, general specificity and character of HIV specific CD8+ T cell responses, showing CD8+ T cell abnormalities in chronic infection.
Tue May 25 00:00:00 EDT 2010
CXCL10 production by human monocytes in response to Leishmania braziliensis infection.
Infection and immunity
Vargas-Inchaustegui DA,Hogg AE,Tulliano G,Llanos-Cuentas A,Arevalo J,Endsley JJ,Soong L
17-7319 was used in Flow cytometry/Cell sorting to investigate whether unbalance production of inflammatory mediators in response to L. braziliensis infection contributes to disease severity, showing that CXCL10 is produced in response to infection.
Fri Jan 01 00:00:00 EST 2010
Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing.
Clinical cancer research : an official journal of the American Association for Cancer Research
Sfanos KS,Bruno TC,Maris CH,Xu L,Thoburn CJ,DeMarzo AM,Meeker AK,Isaacs WB,Drake CG
17-7319 was used in Flow cytometry/Cell sorting to reveal a potential role for TH17 and regulatory CD4+ T cells in the development or progression of prostate cancer.
Sun Jun 01 00:00:00 EDT 2008
cytokine
