Product References
Effects of Extracellular Vesicles Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells on Cell Immunity in Nonobese Mice.
Stem cells international
Ou Y,Yang Y,Wang Y,Su H,Zhou YK
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Feb 13 00:00:00 UTC 2024
Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis.
Nature communications
Lei Y,Guo X,Luo Y,Niu X,Xi Y,Xiao L,He D,Bian Y,Zhang Y,Wang L,Peng X,Wang Z,Chen G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jan 02 00:00:00 UTC 2024
Immune signature of Chlamydia vaccine CTH522/CAF®01 translates from mouse-to-human and induces durable protection in mice.
Nature communications
Olsen AW,Rosenkrands I,Jacobsen CS,Cheeseman HM,Kristiansen MP,Dietrich J,Shattock RJ,Follmann F
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Feb 23 00:00:00 UTC 2024
IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.
Nature communications
Cardinez C,Hao Y,Kwong K,Davies AR,Downes MB,Roberts NA,Price JD,Hernandez RA,Lovell J,Chand R,Feng ZP,Enders A,Vinuesa CG,Miraghazadeh B,Cook MC
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Mar 25 00:00:00 UTC 2024
IL-4 activates ULK1/Atg9a/Rab9 in asthma, NLRP3 inflammasomes, and Golgi fragmentation by increasing autophagy flux and mitochondrial oxidative stress.
Redox biology
Xu C,Song Y,Liu W,Liu R,Bai Q,Li L,Wang C,Yan G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed May 01 00:00:00 UTC 2024
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Metabolic tagging of extracellular vesicles and development of enhanced extracellular vesicle based cancer vaccines.
Nature communications
Bhatta R,Han J,Liu Y,Bo Y,Lee D,Zhou J,Wang Y,Nelson ER,Chen Q,Zhang XS,Hassaneen W,Wang H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 05 00:00:00 UTC 2023
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Immunity
Briukhovetska D,Suarez-Gosalvez J,Voigt C,Markota A,Giannou AD,Schübel M,Jobst J,Zhang T,Dörr J,Märkl F,Majed L,Müller PJ,May P,Gottschlich A,Tokarew N,Lücke J,Oner A,Schwerdtfeger M,Andreu-Sanz D,Grünmeier R,Seifert M,Michaelides S,Hristov M,König LM,Cadilha BL,Mikhaylov O,Anders HJ,Rothenfusser S,Flavell RA,Cerezo-Wallis D,Tejedo C,Soengas MS,Bald T,Huber S,Endres S,Kobold S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jan 10 00:00:00 UTC 2023
Biometabolites of Citrus unshiu Peel Enhance Intestinal Permeability and Alter Gut Commensal Bacteria.
Nutrients
Lee SH,Seo D,Lee KH,Park SJ,Park S,Kim H,Kim T,Joo IH,Park JM,Kang YH,Lim GH,Kim DH,Yang JY
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jan 09 00:00:00 UTC 2023
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma.
EMBO molecular medicine
Wu M,Luo Z,Cai Z,Mao Q,Li Z,Li H,Zhang C,Zhang Y,Zhong A,Wu L,Liu X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Oct 11 00:00:00 UTC 2023
Alleviating psoriatic skin inflammation through augmentation of Treg cells via CTLA-4 signaling peptide.
Frontiers in immunology
Lee WS,Nam KH,Kim JH,Kim WJ,Kim JE,Shin EC,Kim GR,Choi JM
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Oct 12 00:00:00 UTC 2023
Klebsiella pneumoniae Induces Inflammatory Bowel Disease Through Caspase-11-Mediated IL18 in the Gut Epithelial Cells.
Cellular and molecular gastroenterology and hepatology
Zhang Q,Su X,Zhang C,Chen W,Wang Y,Yang X,Liu D,Zhang Y,Yang R
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Feb 23 00:00:00 UTC 2023
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials
Sun S,Li E,Zhao G,Tang J,Zuo Q,Cai L,Xu C,Sui C,Ou Y,Liu C,Li H,Ding Y,Li C,Lu D,Zhang W,Luo P,Cheng P,Gao Y,Tu C,Pitard B,Rosenecker J,Wang B,Liu Y,Zou Q,Guan S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2023
Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self.
Cell reports
Geiger KM,Manoharan M,Coombs R,Arana K,Park CS,Lee AY,Shastri N,Robey EA,Coscoy L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 25 00:00:00 UTC 2023
Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
iScience
Vetters J,van Helden M,De Nolf C,Rennen S,Cloots E,Van De Velde E,Fayazpour F,Van Moorleghem J,Vanheerswynghels M,Vergote K,Boon L,Vivier E,Lambrecht BN,Janssens S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Dec 15 00:00:00 UTC 2023
Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-γ-stimulated antitumor immunity.
The Journal of clinical investigation
Ren J,Li N,Pei S,Lian Y,Li L,Peng Y,Liu Q,Guo J,Wang X,Han Y,Zhang G,Wang H,Li Y,Jiang J,Li Q,Tan M,Peng J,Hu G,Xiao Y,Li X,Lin M,Qin J
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Apr 15 00:00:00 UTC 2022
Epigenomics of conventional type-I dendritic cells depicted preferential control of TLR9 versus TLR3 response by NCoR1 through differential IRF3 activation.
Cellular and molecular life sciences : CMLS
Mishra GP,Jha A,Ahad A,Sen K,Sen A,Podder S,Prusty S,Biswas VK,Gupta B,Raghav SK
25-7311-41 was used in Flow cytometry/Cell sorting to show that, for the first time, we revealed NCoR1 mediates transcriptional control towards TLR9 as compared to TLR3 in cDC1.
Mon Jul 18 00:00:00 UTC 2022
A peptide encoded by pri-miRNA-31 represses autoimmunity by promoting Treg differentiation.
EMBO reports
Zhou H,Lou F,Bai J,Sun Y,Cai W,Sun L,Xu Z,Liu Z,Zhang L,Yin Q,Zhang J,Gao Y,Wang Z,Niu L,Cai X,Deng S,Wang H,Xia L,Ginhoux F,Li Q,Wang H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed May 04 00:00:00 UTC 2022
Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases.
Arthritis research & therapy
Chen YH,Liu RH,Cui YZ,Hettinghouse A,Fu WY,Zhang L,Zhang C,Liu CJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Jan 19 00:00:00 UTC 2022
Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2.
Nature communications
Wilson AS,Randall KL,Pettitt JA,Ellyard JI,Blumenthal A,Enders A,Quah BJ,Bopp T,Parish CR,Brüstle A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Jan 26 00:00:00 UTC 2022
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
International journal of molecular sciences
Yang G,Wang J,Wang S,Zhu Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat Aug 20 00:00:00 UTC 2022
Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer.
eLife
Wang Y,Yang H,Jia A,Wang Y,Yang Q,Dong Y,Hou Y,Cao Y,Dong L,Bi Y,Liu G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Aug 22 00:00:00 UTC 2022
Leishmania donovani Impedes Antileishmanial Immunity by Suppressing Dendritic Cells via the TIM-3 Receptor.
mBio
Akhtar MN,Kumar S,Sen P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Aug 30 00:00:00 UTC 2022
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Nov 15 00:00:00 UTC 2022
Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.
Cell reports
Viladomiu M,Khounlotham M,Dogan B,Lima SF,Elsaadi A,Cardakli E,Castellanos JG,Ng C,Herzog J,Schoenborn AA,Ellermann M,Liu B,Zhang S,Gulati AS,Sartor RB,Simpson KW,Lipkin SM,Longman RS
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Nov 15 00:00:00 UTC 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Feb 16 00:00:00 UTC 2022
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling.
Nature communications
Xie F,Zhou X,Su P,Li H,Tu Y,Du J,Pan C,Wei X,Zheng M,Jin K,Miao L,Wang C,Meng X,van Dam H,Ten Dijke P,Zhang L,Zhou F
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2022
Local and Systemic Injections of Human Cord Blood Myeloid-Derived Suppressor Cells to Prevent Graft Rejection in Corneal Transplantation.
Biomedicines
Lee JY,Sohn HJ,Kim CH,Kim TG,Lee HS
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Dec 12 00:00:00 UTC 2022
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
Immunity
Hall JA,Pokrovskii M,Kroehling L,Kim BR,Kim SY,Wu L,Lee JY,Littman DR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Nov 08 00:00:00 UTC 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 06 00:00:00 UTC 2022
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.
Nature
Zheng J,Wong LR,Li K,Verma AK,Ortiz ME,Wohlford-Lenane C,Leidinger MR,Knudson CM,Meyerholz DK,McCray PB,Perlman S
25-7311 was used in Flow cytometry/Cell sorting to show that K18-hACE2 mice provide a useful model for studying the pathological basis of both mild and lethal COVID-19 and for assessing therapeutic interventions.
Fri Jan 01 00:00:00 UTC 2021
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota.
Cell
Lima-Junior DS,Krishnamurthy SR,Bouladoux N,Collins N,Han SJ,Chen EY,Constantinides MG,Link VM,Lim AI,Enamorado M,Cataisson C,Gil L,Rao I,Farley TK,Koroleva G,Attig J,Yuspa SH,Fischbach MA,Kassiotis G,Belkaid Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Jul 08 00:00:00 UTC 2021
The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice.
Immunity
Shreeve N,Depierreux D,Hawkes D,Traherne JA,Sovio U,Huhn O,Jayaraman J,Horowitz A,Ghadially H,Perry JRB,Moffett A,Sled JG,Sharkey AM,Colucci F
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jun 08 00:00:00 UTC 2021
Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation.
Cell host & microbe
Viladomiu M,Metz ML,Lima SF,Jin WB,Chou L,Guo CJ,Diehl GE,Simpson KW,Scherl EJ,Longman RS
25-7311-41 was used in Flow cytometry/Cell sorting to identify MNPs as metabolic sensors linking AIEC metabolism with intestinal inflammation and identify microbial metabolism as a potential therapeutic target in Crohn's disease treatment.
Wed Apr 14 00:00:00 UTC 2021
The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13.
Cellular & molecular immunology
Mulas F,Wang X,Song S,Nishanth G,Yi W,Brunn A,Larsen PK,Isermann B,Kalinke U,Barragan A,Naumann M,Deckert M,Schlüter D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis.
The Journal of experimental medicine
Ma C,Li S,Hu Y,Ma Y,Wu Y,Wu C,Liu X,Wang B,Hu G,Zhou J,Yang S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon May 03 00:00:00 UTC 2021
Mapping and role of T cell response in SARS-CoV-2-infected mice.
The Journal of experimental medicine
Zhuang Z,Lai X,Sun J,Chen Z,Zhang Z,Dai J,Liu D,Li Y,Li F,Wang Y,Zhu A,Wang J,Yang W,Huang J,Li X,Hu L,Wen L,Zhuo J,Zhang Y,Chen D,Li S,Huang S,Shi Y,Zheng K,Zhong N,Zhao J,Zhou D,Zhao J
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 05 00:00:00 UTC 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Apr 09 00:00:00 UTC 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 13 00:00:00 UTC 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 13 00:00:00 UTC 2021
Senescent T Cell Induces Brown Adipose Tissue "Whitening" Via Secreting IFN-γ.
Frontiers in cell and developmental biology
Pan XX,Yao KL,Yang YF,Ge Q,Zhang R,Gao PJ,Ruan CC,Wu F
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Mar 23 00:00:00 UTC 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Aug 03 00:00:00 UTC 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Nov 07 00:00:00 UTC 2023
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Nov 07 00:00:00 UTC 2023
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis.
Journal of immunology research
Lin Y,Dong Y,Gao Y,Shi R,Li Y,Zhou X,Liu W,Li G,Qi Y,Wu Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Sep 20 00:00:00 UTC 2021
Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice.
Molecular medicine reports
Pang L,Yu P,Liu X,Fan Y,Shi Y,Zou S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Features of T-cell subset composition in a D-galactose-induced senescence mouse model.
Experimental animals
Kawata K,Suzuki T,Ozawa K,Sekiguchi M
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Aug 06 00:00:00 UTC 2021
T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death.
JCI insight
Chun N,Ang RL,Chan M,Fairchild RL,Baldwin WM,Horwitz JK,Gelles JD,Chipuk JE,Kelliher MA,Pavlov VI,Li Y,Homann D,Heeger PS,Ting AT
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Dec 22 00:00:00 UTC 2021
Antitumor efficacy of a neoantigen cancer vaccine delivered by electroporation is influenced by microbiota composition.
Oncoimmunology
Lione L,Salvatori E,Petrazzuolo A,Massacci A,Maggio R,Confroti A,Compagnone M,Aurisicchio L,Ciliberto G,Palombo F
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Mar 23 00:00:00 UTC 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 12 00:00:00 UTC 2021
Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice.
Frontiers in immunology
Prasad M,Wojciech L,Brzostek J,Hu J,Chua YL,Tung DWH,Yap J,Rybakin V,Gascoigne NRJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Sep 23 00:00:00 UTC 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Dec 17 00:00:00 UTC 2021
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity.
The Journal of biological chemistry
Tsai SJ,Atai NA,Cacciottolo M,Nice J,Salehi A,Guo C,Sedgwick A,Kanagavelu S,Gould SJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Nov 01 00:00:00 UTC 2021
Engineered macrophages as near-infrared light activated drug vectors for chemo-photodynamic therapy of primary and bone metastatic breast cancer.
Nature communications
Huang Y,Guan Z,Dai X,Shen Y,Wei Q,Ren L,Jiang J,Xiao Z,Jiang Y,Liu D,Huang Z,Xu X,Luo Y,Zhao C
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Jul 14 00:00:00 UTC 2021
Mechanisms that allow vaccination against an oncolytic vesicular stomatitis virus-encoded transgene to enhance safety without abrogating oncolysis.
Scientific reports
AuYeung AWK,Mould RC,Stegelmeier AA,van Vloten JP,Karimi K,Woods JP,Petrik JJ,Wood GA,Bridle BW
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jul 27 00:00:00 UTC 2021
YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis.
JCI insight
Lin J,Tang J,Lin J,He Y,Yu Z,Jiang R,Yang B,Ou Q
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Nov 22 00:00:00 UTC 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
25-7311-41 was used in Flow Cytometry to provide a protocol for analysis of T cell activation and cytokine production in the thymus, spleen, and blood.
Fri Mar 19 00:00:00 UTC 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
25-7311-41 was used in Flow Cytometry to provide a protocol for analysis of T cell activation and cytokine production in the thymus, spleen, and blood.
Fri Mar 19 00:00:00 UTC 2021
Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores.
International journal of molecular sciences
Tanaka Y,Nakao A,Miyake Y,Higashi Y,Tanigaki R,Kataoka T
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Dec 03 00:00:00 UTC 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
25-7311-41 was used in Flow Cytometry to show that clotrimazole could trigger DC activation via the lactate-lysosome axis to promote antigen cross-presentation and could be used as a potential combination therapy approach to improving the therapeutic efficacy of anti-PD1 immunotherapy.
Sat May 01 00:00:00 UTC 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jun 25 00:00:00 UTC 2021
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance.
Nature communications
Wagle MV,Vervoort SJ,Kelly MJ,Van Der Byl W,Peters TJ,Martin BP,Martelotto LG,Nüssing S,Ramsbottom KM,Torpy JR,Knight D,Reading S,Thia K,Miosge LA,Howard DR,Gloury R,Gabriel SS,Utzschneider DT,Oliaro J,Powell JD,Luciani F,Trapani JA,Johnstone RW,Kallies A,Goodnow CC,Parish IA
25-7311-41 was used in Flow cytometry/Cell sorting to show that persistent antigen recognition drives higher EGR2 expression within exhausted versus effector CD8+T cells.
Thu May 13 00:00:00 UTC 2021
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
eLife
Ramos MIP,Tian L,de Ruiter EJ,Song C,Paucarmayta A,Singh A,Elshof E,Vijver SV,Shaik J,Bosiacki J,Cusumano Z,Jensen C,Willumsen N,Karsdal MA,Liu L,Langermann S,Willems S,Flies D,Meyaard L
25-7311-41 was used in Flow cytometry/Cell sorting to show that NC410 might be a novel strategy for cancer immunotherapy for immune-excluded tumors.
Mon Jun 14 00:00:00 UTC 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jun 25 00:00:00 UTC 2021
Common germline variants of the human APOE gene modulate melanoma progression and survival.
Nature medicine
Ostendorf BN,Bilanovic J,Adaku N,Tafreshian KN,Tavora B,Vaughan RD,Tavazoie SF
25-7311-41 was used in Flow Cytometry to investigate if the human APOE gene is causally involved in melanoma outcome.
Wed Jul 01 00:00:00 UTC 2020
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 15 00:00:00 UTC 2020
The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24.
Immunity
Chong WP,Mattapallil MJ,Raychaudhuri K,Bing SJ,Wu S,Zhong Y,Wang W,Chen Z,Silver PB,Jittayasothorn Y,Chan CC,Chen J,Horai R,Caspi RR
25-7311 was used in Flow cytometry/Cell sorting to report that Th17 cells are regulated by their own signature cytokine, IL-17A.
Tue Aug 18 00:00:00 UTC 2020
Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells.
Immunity
McGinley AM,Sutton CE,Edwards SC,Leane CM,DeCourcey J,Teijeiro A,Hamilton JA,Boon L,Djouder N,Mills KHG
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that a key function of IL-17A in central nervous system (CNS) autoimmunity is to recruit IL-1β-secreting myeloid cells that prime pathogenic γδT17 and Th17 cells.
Tue Feb 18 00:00:00 UTC 2020
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Immunity
DiToro D,Harbour SN,Bando JK,Benavides G,Witte S,Laufer VA,Moseley C,Singer JR,Frey B,Turner H,Bruning J,Darley-Usmar V,Gao M,Conover C,Hatton RD,Frank S,Colonna M,Weaver CT
25-7311 was used in Flow cytometry/Cell sorting to show that, among effector T cell subsets, Th17 and Treg cells selectively expressed multiple components of the IGF system.
Tue Apr 14 00:00:00 UTC 2020
Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors.
EMBO molecular medicine
Fan Z,Tian Y,Chen Z,Liu L,Zhou Q,He J,Coleman J,Dong C,Li N,Huang J,Xu C,Zhang Z,Gao S,Zhou P,Ding K,Chen L
25-7311 was used in Flow cytometry/Cell sorting to determine steps within PD-1 signalling pathway that can be targeted in anticancer drugs.
Mon Jun 08 00:00:00 UTC 2020
Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis.
Autophagy
Pahari S,Negi S,Aqdas M,Arnett E,Schlesinger LS,Agrewala JN
25-7311-41 was used in Flow Cytometry to invesigate if a unique immunotherapeutic approach involving CLEC4E in conjunction with TLR4 to restrict the survival of mycobacterium tuberculosis through autophagy exists.
Mon Jun 01 00:00:00 UTC 2020
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
The Journal of cell biology
Xu X,Hou B,Fulzele A,Masubuchi T,Zhao Y,Wu Z,Hu Y,Jiang Y,Ma Y,Wang H,Bennett EJ,Fu G,Hui E
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jun 01 00:00:00 UTC 2020
Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.
PLoS pathogens
Akhtar MN,Mishra M,Yadav V,Yadav M,Gujar R,Lal S,Kumar R,Khatri N,Sen P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate.
Veterinary research
Sisteré-Oró M,Pedersen GK,Córdoba L,López-Serrano S,Christensen D,Darji A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 20 00:00:00 UTC 2020
Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine candidate.
Veterinary research
Sisteré-Oró M,Pedersen GK,Córdoba L,López-Serrano S,Christensen D,Darji A
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 20 00:00:00 UTC 2020
Expression of CD27 and CD28 on γδ T cells from the peripheral blood of patients with allergic rhinitis.
Experimental and therapeutic medicine
Wang Q,Sun Q,Chen Q,Li H,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection.
Experimental and therapeutic medicine
Chang L,Wang L,Ling N,Peng H,Chen M
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2020
Isolation and functional characterisation of lamina propria leukocytes from helminth-infected, murine small intestine.
Journal of immunological methods
Webster HC,Andrusaite AT,Shergold AL,Milling SWF,Perona-Wright G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat Feb 01 00:00:00 UTC 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 27 00:00:00 UTC 2020
C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.
Frontiers in immunology
Briukhovetska D,Ohm B,Mey FT,Aliberti J,Kleingarn M,Huber-Lang M,Karsten CM,Köhl J
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 05 00:00:00 UTC 2021
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 14 00:00:00 UTC 2020
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.
NPJ vaccines
Brar G,Farhat NA,Sukhina A,Lam AK,Kim YH,Hsu T,Tong L,Lin WW,Ware CF,Blackman MA,Sun R,Wu TT
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Nov 05 00:00:00 UTC 2020
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Jun 11 00:00:00 UTC 2020
BCG vaccination reduces the mortality of Mycobacterium tuberculosis-infected type 2 diabetes mellitus mice.
JCI insight
Radhakrishnan RK,Thandi RS,Tripathi D,Paidipally P,McAllister MK,Mulik S,Samten B,Vankayalapati R
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Mar 12 00:00:00 UTC 2020
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Nature communications
Mahata B,Pramanik J,van der Weyden L,Polanski K,Kar G,Riedel A,Chen X,Fonseca NA,Kundu K,Campos LS,Ryder E,Duddy G,Walczak I,Okkenhaug K,Adams DJ,Shields JD,Teichmann SA
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jul 17 00:00:00 UTC 2020
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Cell communication and signaling : CCS
Klepsch V,Pommermayr M,Humer D,Brigo N,Hermann-Kleiter N,Baier G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jan 14 00:00:00 UTC 2020
TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response.
Nature communications
Chen J,He R,Sun W,Gao R,Peng Q,Zhu L,Du Y,Ma X,Guo X,Zhang H,Tan C,Wang J,Zhang W,Weng X,Man J,Bauer H,Wang QK,Martin BN,Zhang CJ,Li X,Wang C
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 20 00:00:00 UTC 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Aug 27 00:00:00 UTC 2020
PCC0208025 (BMS202), a small molecule inhibitor of PD-L1, produces an antitumor effect in B16-F10 melanoma-bearing mice.
PloS one
Hu Z,Yu P,Du G,Wang W,Zhu H,Li N,Zhao H,Dong Z,Ye L,Tian J
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jun 22 00:00:00 UTC 2020
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia.
bioRxiv : the preprint server for biology
Zheng J,Roy Wong LY,Li K,Verma AK,Ortiz M,Wohlford-Lenane C,Leidinger MR,Knudson CM,Meyerholz DK,McCray PB,Perlman S
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that K18-hACE2 mice provide a useful model for studying the pathological underpinnings of both mild and lethal COVID-19 and for assessing therapeutic interventions.
Mon Aug 10 00:00:00 UTC 2020
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.
Cell reports
Yang YH,Istomine R,Alvarez F,Al-Aubodah TA,Shi XQ,Takano T,Thornton AM,Shevach EM,Zhang J,Piccirillo CA
25-7311-41 was used in Flow Cytometry to show that high salt (HS) drives thymic Treg cells to adopt a T helper type 17 (Th17)-like phenotype and enhances generation of Th17-like induced Treg cells in a SGK1-dependent manner, all the while maintaining suppressive function.
Tue Feb 04 00:00:00 UTC 2020
Bmal1 integrates mitochondrial metabolism and macrophage activation.
eLife
Alexander RK,Liou YH,Knudsen NH,Starost KA,Xu C,Hyde AL,Liu S,Jacobi D,Liao NS,Lee CH
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue May 12 00:00:00 UTC 2020
CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.
Nature communications
Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ
25-7311 was used in Flow cytometry/Cell sorting to demonstrate the stimulatory effect of CD40L-overexpressing CAR T cells on innate and adaptive immune cells, and provide a rationale for using CD40L-overexpressing CAR T cells to improve immunotherapy responses.
Wed Dec 02 00:00:00 UTC 2020
Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Frontiers in immunology
Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR
25-7311 was used in Flow cytometry/Cell sorting to show dendritic cell PTPN2 might explain the central role for PTPN2 in the immune system to maintain immune tolerance.
Mon Apr 12 00:00:00 UTC 2021
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides.
Frontiers in immunology
Pfeil J,Simonetti M,Lauer U,Volkmer R,von Thülen B,Durek P,Krähmer R,Leenders F,Hamann A,Hoffmann U
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Apr 29 00:00:00 UTC 2021
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides.
Frontiers in immunology
Pfeil J,Simonetti M,Lauer U,Volkmer R,von Thülen B,Durek P,Krähmer R,Leenders F,Hamann A,Hoffmann U
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Apr 29 00:00:00 UTC 2021
Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells.
Cell reports
Dodard G,Tata A,Erick TK,Jaime D,Miah SMS,Quatrini L,Escalière B,Ugolini S,Vivier E,Brossay L
25-7311 was used in Flow cytometry/Cell sorting to characterize the kinetics and immune response of each of the hepatic NK cell populations to viral challenge and other stimuli.
Tue Jul 07 00:00:00 UTC 2020
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Frontiers in immunology
Yu Y,Wu DM,Li J,Deng SH,Liu T,Zhang T,He M,Zhao YY,Xu Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jun 21 00:00:00 UTC 2021
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Cancer cell
Jackstadt R,van Hooff SR,Leach JD,Cortes-Lavaud X,Lohuis JO,Ridgway RA,Wouters VM,Roper J,Kendall TJ,Roxburgh CS,Horgan PG,Nixon C,Nourse C,Gunzer M,Clark W,Hedley A,Yilmaz OH,Rashid M,Bailey P,Biankin AV,Campbell AD,Adams DJ,Barry ST,Steele CW,Medema JP,Sansom OJ
25-7311-41 was used in Flow Cytometry to propose that NOTCH1 signaling is key to CRC progression and should be exploited clinically.
Mon Sep 16 00:00:00 UTC 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
25-7311 was used in Flow cytometry/Cell sorting to show that teniposide could trigger tumor immunogenicity and enable a potential chemoimmunotherapeutic approach to potentiating the therapeutic efficacy of anti-PD1 immunotherapy.
Tue Aug 13 00:00:00 UTC 2019
Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.
The Journal of experimental medicine
Etzerodt A,Tsalkitzi K,Maniecki M,Damsky W,Delfini M,Baudoin E,Moulin M,Bosenberg M,Graversen JH,Auphan-Anezin N,Moestrup SK,Lawrence T
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Oct 07 00:00:00 UTC 2019
Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers.
Cancer research
Bhatia S,Oweida A,Lennon S,Darragh LB,Milner D,Phan AV,Mueller AC,Van Court B,Raben D,Serkova NJ,Wang XJ,Jimeno A,Clambey ET,Pasquale EB,Karam SD
25-7311 was used in Flow cytometry/Cell sorting to show EphB4-ephrin-B2 inhibition displayed tumor growth suppression, indicating a possible alternative for those that cannot receive anti-PDL1 therapy.
Wed May 15 00:00:00 UTC 2019
BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis.
Oncogene
Das S,Bar-Sagi D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Apr 01 00:00:00 UTC 2019
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2019
CD8+ T cells promote cytokine responses to stress.
Cytokine
Clark SM,Song C,Li X,Keegan AD,Tonelli LH
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jan 01 00:00:00 UTC 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jan 15 00:00:00 UTC 2019
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
NPJ vaccines
Li G,Adam A,Luo H,Shan C,Cao Z,Fontes-Garfias CR,Sarathy VV,Teleki C,Winkelmann ER,Liang Y,Sun J,Bourne N,Barrett ADT,Shi PY,Wang T
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.
Frontiers in immunology
Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Oct 14 00:00:00 UTC 2020
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Mar 20 00:00:00 UTC 2019
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Nature communications
Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Nov 28 00:00:00 UTC 2019
Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.
Cell reports
Fu Z,Ye J,Dean JW,Bostick JW,Weinberg SE,Xiong L,Oliff KN,Chen ZE,Avram D,Chandel NS,Zhou L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jul 02 00:00:00 UTC 2019
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.
Cell reports
Anderson CK,Reilly EC,Lee AY,Brossay L
25-7311 was used in Flow cytometry/Cell sorting to study compensatory mechanisms in immune responses to viruses when classical T cell immunity has been evaded.
Tue Apr 09 00:00:00 UTC 2019
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.
Nature communications
Scheer S,Ackloo S,Medina TS,Schapira M,Li F,Ward JA,Lewis AM,Northrop JP,Richardson PL,Kaniskan HÜ,Shen Y,Liu J,Smil D,McLeod D,Zepeda-Velazquez CA,Luo M,Jin J,Barsyte-Lovejoy D,Huber KVM,De Carvalho DD,Vedadi M,Zaph C,Brown PJ,Arrowsmith CH
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Jan 03 00:00:00 UTC 2019
Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity.
Nature microbiology
David SC,Norton T,Tyllis T,Wilson JJ,Singleton EV,Laan Z,Davies J,Hirst TR,Comerford I,McColl SR,Paton JC,Alsharifi M
25-7311 was used in Flow cytometry/Cell sorting to provide an additional explanation for the synergistic pathogenicity of IAV and S. pneumoniae, as well as heralding the prospect of exploiting the phenomenon to develop better vaccine strategies for both pathogens.
Thu Aug 01 00:00:00 UTC 2019
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.
Nature communications
Yasuda K,Kitagawa Y,Kawakami R,Isaka Y,Watanabe H,Kondoh G,Kohwi-Shigematsu T,Sakaguchi S,Hirota K
25-7311-41 was used in Flow Cytometry to indicate that Satb1 regulates the specific gene expression and function of effector Th17 cells in tissue inflammation.
Fri Feb 01 00:00:00 UTC 2019
Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology.
NPJ vaccines
Orr MT,Khandhar AP,Seydoux E,Liang H,Gage E,Mikasa T,Beebe EL,Rintala ND,Persson KH,Ahniyaz A,Carter D,Reed SG,Fox CB
25-7311 was used in Flow cytometry/Cell sorting to determine whether the particle size and aggregated state of aluminum oxyhydroxide affects its adjuvant activity.
Thu Oct 01 00:00:00 UTC 2020
Innate-Like Lymphocytes Are Immediate Participants in the Hyper-Acute Immune Response to Trauma and Hemorrhagic Shock.
Frontiers in immunology
Manson J,Hoffman R,Chen S,Ramadan MH,Billiar TR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 13 00:00:00 UTC 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Jan 25 00:00:00 UTC 2018
Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.
Cell
Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Jun 28 00:00:00 UTC 2018
SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
Immunity
Malik A,Sharma D,Malireddi RKS,Guy CS,Chang TC,Olsen SR,Neale G,Vogel P,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Sep 18 00:00:00 UTC 2018
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Immunity
Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jun 19 00:00:00 UTC 2018
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells.
Nature immunology
Gabryšová L,Alvarez-Martinez M,Luisier R,Cox LS,Sodenkamp J,Hosking C,Pérez-Mazliah D,Whicher C,Kannan Y,Potempa K,Wu X,Bhaw L,Wende H,Sieweke MH,Elgar G,Wilson M,Briscoe J,Metzis V,Langhorne J,Luscombe NM,O'Garra A
25-7311 was used in Flow cytometry/Cell sorting to study the role of c-Maf as a regulator of the expression of cytokine-encoding genes.
Tue May 01 00:00:00 UTC 2018
Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function.
British journal of pharmacology
Lu Y,Kim NM,Jiang YW,Zhang H,Zheng D,Zhu FX,Liang R,Li B,Xu HX
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sun Apr 01 00:00:00 UTC 2018
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
25-7311-41 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 UTC 2019
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Feb 01 00:00:00 UTC 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
mTOR Modulates CD8+ T Cell Differentiation in Mice with Invasive Pulmonary Aspergillosis.
Open life sciences
Wang H,Xiao Y,Su L,Cui N,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jan 01 00:00:00 UTC 2018
Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells.
Frontiers in cellular neuroscience
Osorio-Barrios F,Prado C,Contreras F,Pacheco R
25-7311 was used in Flow cytometry/Cell sorting to indicate a complex role for DRD5-signalling in CD4+ T-cells-driven responses potentiating early inflammation mediated by effector T-cells in experimental autoimmune encephalomyelitis.
Thu Oct 01 00:00:00 UTC 2020
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Mar 28 00:00:00 UTC 2018
Nicotinamide adenine dinucleotide phosphate (reduced) oxidase 2 modulates inflammatory vigor during nonalcoholic fatty liver disease progression in mice.
Hepatology communications
Mukherjee R,Moreno-Fernandez ME,Giles DA,Cappelletti M,Stankiewicz TE,Chan CC,Divanovic S
25-7311 was used in Flow cytometry/Cell sorting to demonstrate a crucial role of the NOX2-ROS axis in immune cell effector function and polarization and consequent NAFLD progression in obesity.
Tue May 01 00:00:00 UTC 2018
Trichinella spiralis Infection Mitigates Collagen-Induced Arthritis via Programmed Death 1-Mediated Immunomodulation.
Frontiers in immunology
Cheng Y,Zhu X,Wang X,Zhuang Q,Huyan X,Sun X,Huang J,Zhan B,Zhu X
25-7311 was used in Flow cytometry/Cell sorting to introduce the first evidence that PD-1 plays a critical role in Trichinella spiralis infection-attenuated collagen-induced arthritis in a mouse model by regulating the CD4+ T cell function, which may provide the new insights into the mechanisms of helminth-induced immunomodulation of host autoimmunity.
Mon Jan 28 00:00:00 UTC 2019
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
JCI insight
Moreno-Fernandez ME,Giles DA,Stankiewicz TE,Sheridan R,Karns R,Cappelletti M,Lampe K,Mukherjee R,Sina C,Sallese A,Bridges JP,Hogan SP,Aronow BJ,Hoebe K,Divanovic S
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Mar 22 00:00:00 UTC 2018
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis.
Nature communications
Kim DH,Park HJ,Lim S,Koo JH,Lee HG,Choi JO,Oh JH,Ha SJ,Kang MJ,Lee CM,Lee CG,Elias JA,Choi JM
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Feb 05 00:00:00 UTC 2018
Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Nature communications
Chandra S,Gray J,Kiosses WB,Khurana A,Hitomi K,Crosby CM,Chawla A,Fu Z,Zhao M,Veerapen N,Richardson SK,Porcelli SA,Besra G,Howell AR,Sharma S,Peters B,Kronenberg M
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Oct 15 00:00:00 UTC 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Nov 08 00:00:00 UTC 2018
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
25-7311 was used in Flow cytometry/Cell sorting to demonstrate the importance of ATB2 cells in obesity-induced insulin resistance and suggest that inhibition of the LTB4/LTB4R1 axis might be a useful approach for developing insulin-sensitising therapeutics.
Wed Mar 01 00:00:00 UTC 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Apr 12 00:00:00 UTC 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jun 05 00:00:00 UTC 2017
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.
Gut microbes
Jacobs JP,Lin L,Goudarzi M,Ruegger P,McGovern DP,Fornace AJ,Borneman J,Xia L,Braun J
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jan 02 00:00:00 UTC 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Nov 20 00:00:00 UTC 2019
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Mucosal immunology
Qi X,Gurung P,Malireddi RK,Karmaus PW,Sharma D,Vogel P,Chi H,Green DR,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2017
Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses.
Mucosal immunology
Christensen D,Mortensen R,Rosenkrands I,Dietrich J,Andersen P
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that subcutaneous priming with a recombinant antigen in a T helper (Th)17-inducing adjuvant followed by airway boosting promotes high and sustained levels of IgA in the lungs.
Sun Jan 01 00:00:00 UTC 2017
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
25-7311 was used in Flow cytometry/Cell sorting to suggest that MyD88 signaling in DC and IEC is both essential and sufficient to induce a full spectrum of host responses upon intestinal infection with C. rodentium.
Mon May 01 00:00:00 UTC 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat May 20 00:00:00 UTC 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2017
An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology.
Scientific reports
Clemmensen HS,Knudsen NPH,Rasmussen EM,Winkler J,Rosenkrands I,Ahmad A,Lillebaek T,Sherman DR,Andersen PL,Aagaard C
25-7311 was used in Flow cytometry/Cell sorting to investigate the Mycobacterium tuberculosis (M.tb) DK9897 strain, showing that it is attenuated and has a defect in ESX-1 secretion, leading to minimal host immune response and pathology.
Mon Apr 24 00:00:00 UTC 2017
Culture supernatant of adipose stem cells can ameliorate allergic airway inflammation via recruitment of CD4+CD25+Foxp3 T cells.
Stem cell research & therapy
Yu HS,Park MK,Kang SA,Cho KS,Mun SJ,Roh HJ
25-7311 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which adipose tissue stem cells (ASCs) reduce allergic symptoms and eosinophilic inflammation following injection, showing that culture supernatant of ASCs also reduced allergic airway inflammation.
Mon Jan 23 00:00:00 UTC 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Feb 06 00:00:00 UTC 2017
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon May 21 00:00:00 UTC 2018
Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.
PloS one
Pardo E,Cárcamo C,Uribe-San Martín R,Ciampi E,Segovia-Miranda F,Curkovic-Peña C,Montecino F,Holmes C,Tichauer JE,Acuña E,Osorio-Barrios F,Castro M,Cortes P,Oyanadel C,Valenzuela DM,Pacheco R,Naves R,Soza A,González A
25-7311 was used in Flow cytometry/Cell sorting to reveal that Gal-8 has an immunosuppressive protective role against autoimmune CNS inflammation, modulating the balance of Th17 and Th1 polarisation and their respective Tregs.
Wed Sep 20 00:00:00 UTC 2017
The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma.
Oncotarget
Cho JH,Lee HJ,Ko HJ,Yoon BI,Choe J,Kim KC,Hahn TW,Han JA,Choi SS,Jung YM,Lee KH,Lee YS,Jung YJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 11 00:00:00 UTC 2017
Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation.
Cell host & microbe
Gimblet C,Meisel JS,Loesche MA,Cole SD,Horwinski J,Novais FO,Misic AM,Bradley CW,Beiting DP,Rankin SC,Carvalho LP,Carvalho EM,Scott P,Grice EA
25-7311-41 was used in Flow Cytometry to investigate the role of skin microbiota in cutaneous leishmaniasis and found that human patients infected with Leishmania braziliensis develop dysbiotic skin microbiota, characterized by increases in the abundance of Staphylococcus and/or Streptococcus.
Wed Jul 12 00:00:00 UTC 2017
Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice.
JCI insight
Robert R,Ang C,Sun G,Juglair L,Lim EX,Mason LJ,Payne NL,Bernard CC,Mackay CR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Aug 03 00:00:00 UTC 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.
Scientific reports
Ano Y,Ikado K,Shindo K,Koizumi H,Fujiwara D
25-7311 was used in Flow cytometry/Cell sorting to investigate if 14-dehydroergosterol induces tolerogenic dendritic cells (DCs) to convert to a tolerogenic type.
Tue Oct 24 00:00:00 UTC 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2017
NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
Nature
Karki R,Man SM,Malireddi RKS,Kesavardhana S,Zhu Q,Burton AR,Sharma BR,Qi X,Pelletier S,Vogel P,Rosenstiel P,Kanneganti TD
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Dec 22 00:00:00 UTC 2016
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Oct 06 00:00:00 UTC 2016
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Aug 25 00:00:00 UTC 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue May 17 00:00:00 UTC 2016
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Nature immunology
Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance.
European journal of immunology
Tibbitt C,Falconer J,Stoop J,van Eden W,Robinson JH,Hilkens CM
25-7311 was used in Flow cytometry/Cell sorting to investigate how citrullination of an immunedominant T-cell epitope affects Th17 development.
Fri Jul 01 00:00:00 UTC 2016
IL-12 and IL-4 activate a CD39-dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells.
European journal of immunology
Noble A,Mehta H,Lovell A,Papaioannou E,Fairbanks L
25-7311 was used in Flow cytometry/Cell sorting to study the upregulation of CD39 on CD8(+) T cells and identify a novel pathway of peripheral tolerance.
Wed Jun 01 00:00:00 UTC 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
25-7311 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 UTC 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
25-7311 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 UTC 2016
Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function.
Journal of immunology (Baltimore, Md. : 1950)
Yang E,Singh BK,Paustian AM,Kambayashi T
25-7311 was used in Flow cytometry/Cell sorting to investigate methods to enhance NK cell function, showing that diacylglycerol kinase ζ is a target for enhancement of NK function.
Mon Aug 01 00:00:00 UTC 2016
Low-Dose Intestinal Trichuris muris Infection Alters the Lung Immune Microenvironment and Can Suppress Allergic Airway Inflammation.
Infection and immunity
Chenery AL,Antignano F,Burrows K,Scheer S,Perona-Wright G,Zaph C
25-7311 was used in Flow cytometry/Cell sorting to study crosstalk between the intestine and lung during disease, showing that low-dose intestinal Trichuris muris infection alters the lung immune microenvironment.
Mon Feb 01 00:00:00 UTC 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis.
Biology open
Salao K,Jiang L,Li H,Tsai VW,Husaini Y,Curmi PM,Brown LJ,Brown DA,Breit SN
25-7311 was used in Flow cytometry/Cell sorting to suggest that CLIC1 regulates DC phagosomal pH to ensure optimal processing of antigen for presentation to antigen-specific T-cells.
Sun May 15 00:00:00 UTC 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
25-7311 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 UTC 2016
A Toll-like receptor 2 agonist-fused antigen enhanced antitumor immunity by increasing antigen presentation and the CD8 memory T cells population.
Oncotarget
Wu CC,Liu SJ,Chen HW,Shen KY,Leng CH
25-7311 was used in Flow cytometry/Cell sorting to explore the use of TLR2 agonist-fused antigens for efficient cancer therapy.
Tue May 24 00:00:00 UTC 2016
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
PloS one
Singh S,Vedi S,Samrat SK,Li W,Kumar R,Agrawal B
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Jul 19 00:00:00 UTC 2016
Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models.
Scientific reports
Yang L,Cai C,Feng Q,Shi Y,Zuo Q,Yang H,Jing H,Wei C,Zhuang Y,Zou Q,Zeng H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Feb 11 00:00:00 UTC 2016
Reprogramming the immunological microenvironment through radiation and targeting Axl.
Nature communications
Aguilera TA,Rafat M,Castellini L,Shehade H,Kariolis MS,Hui AB,Stehr H,von Eyben R,Jiang D,Ellies LG,Koong AC,Diehn M,Rankin EB,Graves EE,Giaccia AJ
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Dec 23 00:00:00 UTC 2016
IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease.
Nature communications
Tosiek MJ,Fiette L,El Daker S,Eberl G,Freitas AA
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Mar 11 00:00:00 UTC 2016
NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Nature communications
Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Wed Sep 07 00:00:00 UTC 2016
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.
Journal for immunotherapy of cancer
Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M
25-7311 was used in Flow cytometry/Cell sorting to provide preclinical evidence for the use of anti-GITR (1) non-depleting antibodies in combination with SRS in GBM.
Wed May 18 00:00:00 UTC 2016
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology
Chen HJ,Sun J,Huang Z,Hou H,Arcilla M,Rakhilin N,Joe DJ,Choi J,Gadamsetty P,Milsom J,Nandakumar G,Longman R,Zhou XK,Edwards R,Chen J,Chen KY,Bu P,Wang L,Xu Y,Munroe R,Abratte C,Miller AD,Gümüş ZH,Shuler M,Nishimura N,Edelmann W,Shen X,Lipkin SM
25-7311 was used in Flow cytometry/Cell sorting to create chemokine-targeted mouse models that recapitulate the majority of common human somatic CRC mutations.
Mon Jun 01 00:00:00 UTC 2015
Identification of natural RORγ ligands that regulate the development of lymphoid cells.
Cell metabolism
Santori FR,Huang P,van de Pavert SA,Douglass EF,Leaver DJ,Haubrich BA,Keber R,Lorbek G,Konijn T,Rosales BN,Rozman D,Horvat S,Rahier A,Mebius RE,Rastinejad F,Nes WD,Littman DR
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Feb 03 00:00:00 UTC 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 29 00:00:00 UTC 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jul 10 00:00:00 UTC 2015
The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages.
eLife
Park C,Arthos J,Cicala C,Kehrl JH
25-7311 was used in Flow cytometry/Cell sorting to reveal a specialised lymph node antigen delivery system capable of delivering gp120 and other pathogen-derived glycoproteins to B cells.
Mon Aug 10 00:00:00 UTC 2015
Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.
PLoS pathogens
Wiesner DL,Specht CA,Lee CK,Smith KD,Mukaremera L,Lee ST,Lee CG,Elias JA,Nielsen JN,Boulware DR,Bohjanen PR,Jenkins MK,Levitz SM,Nielsen K
25-7311 was used in Flow cytometry/Cell sorting to investigate Th2 cell responses to pulmonary fungal infection, showing that chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.
Sun Mar 01 00:00:00 UTC 2015
The NF-κB regulator Bcl-3 modulates inflammation during contact hypersensitivity reactions in radioresistant cells.
European journal of immunology
Tassi I,Rikhi N,Claudio E,Wang H,Tang W,Ha HL,Saret S,Kaplan DH,Siebenlist U
25-7311 was used in Flow cytometry/Cell sorting to identify Bcl-3 as critical during contact hypersensitivity reactions to limit inflammation via actions in radioresistant cells.
Wed Apr 01 00:00:00 UTC 2015
IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Arbelaez CA,Glatigny S,Duhen R,Eberl G,Oukka M,Bettelli E
25-7311 was used in Flow cytometry/Cell sorting to address the contribution of IL-23/IL-23R and IL-7/IL-7R signaling in Th17 and Th1 cell dynamics during CNS autoimmunity.
Tue Sep 01 00:00:00 UTC 2015
Leptin receptor signaling in T cells is required for Th17 differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Reis BS,Lee K,Fanok MH,Mascaraque C,Amoury M,Cohn LB,Rogoz A,Dallner OS,Moraes-Vieira PM,Domingos AI,Mucida D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jun 01 00:00:00 UTC 2015
IκBNS regulates murine Th17 differentiation during gut inflammation and infection.
Journal of immunology (Baltimore, Md. : 1950)
Annemann M,Wang Z,Plaza-Sirvent C,Glauben R,Schuster M,Ewald Sander F,Mamareli P,Kühl AA,Siegmund B,Lochner M,Schmitz I
25-7311 was used in Flow cytometry/Cell sorting to study the role of nuclear IκBNS in murine Th17 cell generation upon inflammation and infection.
Sun Mar 15 00:00:00 UTC 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Sep 12 00:00:00 UTC 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon May 16 00:00:00 UTC 2016
Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice.
Human vaccines & immunotherapeutics
Li X,Xu J,Lv Z,Wang J,Sun S,Zhu W,Wang B,He R,Qu D
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Apr 19 00:00:00 UTC 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Mar 11 00:00:00 UTC 2016
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules.
Gene therapy
Rodriguez-Peña AB,Gomez-Rodriguez J,Kortum RL,Palmer DC,Yu Z,Guittard GC,Wohlfert EA,Silver PB,Misplon JA,Sommers CL,Feigenbaum L,Epstein SL,Caspi RR,Belkaid Y,Restifo NP,Samelson LE,Balagopalan L
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2015
Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents.
Scientific reports
Guo A,He D,Xu HB,Geng CA,Zhao J
25-7311 was used in Flow cytometry/Cell sorting to study how the promotion of regulatory T cell induction could be an underlying mechanism of the herbal medicine licorice.
Tue Sep 15 00:00:00 UTC 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Cell reports
Hermann-Kleiter N,Klepsch V,Wallner S,Siegmund K,Klepsch S,Tuzlak S,Villunger A,Kaminski S,Pfeifhofer-Obermair C,Gruber T,Wolf D,Baier G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Sep 29 00:00:00 UTC 2015
Identification and characterization of latency-associated peptide-expressing γδ T cells.
Nature communications
Rezende RM,da Cunha AP,Kuhn C,Rubino S,M'Hamdi H,Gabriely G,Vandeventer T,Liu S,Cialic R,Pinheiro-Rosa N,Oliveira RP,Gaublomme JT,Obholzer N,Kozubek J,Pochet N,Faria AMC,Weiner HL
25-7311 was used in Flow cytometry/Cell sorting to describe a subset of regulatory γδ T cells that express the latency-associated peptide, a membrane-bound TGF-β1.
Tue Dec 08 00:00:00 UTC 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 08 00:00:00 UTC 2015
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Dec 08 00:00:00 UTC 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue May 24 00:00:00 UTC 2016
An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment.
Blood
Gibbins JD,Ancelet LR,Weinkove R,Compton BJ,Painter GF,Petersen TR,Hermans IF
25-7311 was used in Flow cytometry/Cell sorting to investigate the efficacy of an intravenously administered vaccine consisting of irradiated leukemia cells loaded with α-GalCer.
Thu Nov 06 00:00:00 UTC 2014
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
The Journal of experimental medicine
Longman RS,Diehl GE,Victorio DA,Huh JR,Galan C,Miraldi ER,Swaminath A,Bonneau R,Scherl EJ,Littman DR
25-7311 was used in Flow cytometry/Cell sorting to study the role of CX3CR1+ mononuclear phagocytes in the development of colitis and disease progression following Citrobacter rodentium infection.
Mon Jul 28 00:00:00 UTC 2014
Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanism.
Cancer research
Cheng M,Qian L,Shen G,Bian G,Xu T,Xu W,Shen G,Hu S
25-7311 was used in Flow cytometry/Cell sorting to investigate the mechanism by which commensal bacteria modulate the efficiency of tumoral immune surveillance in mucosal tissues.
Fri Aug 01 00:00:00 UTC 2014
Large T Antigen-Specific Cytotoxic T Cells Protect Against Dendritic Cell Tumors through Perforin-Mediated Mechanisms Independent of CD4 T Cell Help.
Frontiers in immunology
Duval A,Fuertes Marraco SA,Schwitter D,Leuenberger L,Acha-Orbea H
25-7311 was used in Flow cytometry/Cell sorting to observe that after transfer into syngeneic C57BL/6 mice, MuTuDC lines were quickly rejected.
Thu Aug 07 00:00:00 UTC 2014
Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium.
Mucosal immunology
Wang Z,Friedrich C,Hagemann SC,Korte WH,Goharani N,Cording S,Eberl G,Sparwasser T,Lochner M
25-7311 was used in Flow cytometry/Cell sorting to study the impact of Foxp3(+) Tregs on inflammatory processes elicited by the bacterial pathogen C. rodentium, showing that Tregs promote a protective Th17-associated immune response.
Sat Nov 01 00:00:00 UTC 2014
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.
European journal of immunology
Reba SM,Li Q,Onwuzulike S,Ding X,Karim AF,Hernandez Y,Fulton SA,Harding CV,Lancioni CL,Nagy N,Rodriguez ME,Wearsch PA,Rojas RE
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Thu May 01 00:00:00 UTC 2014
High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection.
European journal of immunology
Lindenstrøm T,Aagaard C,Christensen D,Agger EM,Andersen P
25-7311 was used in Flow cytometry/Cell sorting to study the role of CD8 T cells in resistance to mycobacterial infections.
Sun Jun 01 00:00:00 UTC 2014
The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950)
Tassi I,Claudio E,Wang H,Tang W,Ha HL,Saret S,Ramaswamy M,Siegel R,Siebenlist U
25-7311 was used in Flow cytometry/Cell sorting to study the role of Bcl-3 in dendritic cell survival and the generation of adaptive immunity.
Sat Nov 01 00:00:00 UTC 2014
Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950)
Huang W,Qi Q,Hu J,Huang F,Laufer TM,August A
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that dendritic cells-MHCII and IL-2-inducible T cell kinase regulate the functional development of IMP CD4(+) T cells.
Tue Apr 01 00:00:00 UTC 2014
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.
Journal of immunology (Baltimore, Md. : 1950)
Donnelly RP,Loftus RM,Keating SE,Liou KT,Biron CA,Gardiner CM,Finlay DK
25-7311 was used in Flow cytometry/Cell sorting to investigate whether mTORC1-controlled metabolism underpins normal natural killer cell proinflammatory functions.
Sat Nov 01 00:00:00 UTC 2014
Preemptive donor apoptotic cell infusions induce IFN-γ-producing myeloid-derived suppressor cells for cardiac allograft protection.
Journal of immunology (Baltimore, Md. : 1950)
Bryant J,Lerret NM,Wang JJ,Kang HK,Tasch J,Zhang Z,Luo X
25-7311 was used in Flow cytometry/Cell sorting to investigate the role of MDSCs in the graft protection provided by ECDI-SPs, showing that preemptive donor apoptotic cell infusions induce IFN-γ-producing MDSCs.
Sun Jun 15 00:00:00 UTC 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Jan 05 00:00:00 UTC 2015
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Mar 06 00:00:00 UTC 2020
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
25-7311 was used in Flow cytometry/Cell sorting to demonstrate plasticity in the CD4(+) T cell lineage that allows chronic exposure to luminal antigens without pathological inflammation.
Fri Mar 01 00:00:00 UTC 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2013
Cytotoxic response persists in subjects treated for tuberculosis decades ago.
BMC infectious diseases
Savolainen LE,Koskivirta P,Kantele A,Valleala H,Pusa L,Tuompo R,Westerlund-Wikström B,Tuuminen T
25-7311 was used in Flow cytometry/Cell sorting to evaluate the influence of various anti-TB therapeutic schemes on the immunological profiles of residual cytotoxic T lymphocytes.
Thu Dec 05 00:00:00 UTC 2013
Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.
PloS one
Obregón-Henao A,Henao-Tamayo M,Orme IM,Ordway DJ
25-7311 was used in Immunofluorescence to compare the bacterial burden, lung pathology and Gr1(int)CD11b(+) myeloid-derived suppressor cell immune responses in M. tuberculosis infected mice.
Fri Jun 20 00:00:00 UTC 2014
Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection.
PloS one
Carbo A,Bassaganya-Riera J,Pedragosa M,Viladomiu M,Marathe M,Eubank S,Wendelsdorf K,Bisset K,Hoops S,Deng X,Alam M,Kronsteiner B,Mei Y,Hontecillas R
25-7311 was used in Flow cytometry/Cell sorting to investigate how CD4+ T-cells and other immune cell subsets are distributed in the gut mucosa during Helicobacter pylori infection.
Sat Jun 07 00:00:00 UTC 2014
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis.
Nature biotechnology
Getts DR,Martin AJ,McCarthy DP,Terry RL,Hunter ZN,Yap WT,Getts MT,Pleiss M,Luo X,King NJ,Shea LD,Miller SD
25-7311 was used in Flow cytometry/Cell sorting to highlight the potential for using microparticles to target natural apoptotic clearance pathways to inactivate pathogenic T cells in autoimmunity.
Sat Dec 01 00:00:00 UTC 2012
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
25-7311 was used in Flow cytometry/Cell sorting to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 UTC 2012
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.
Journal of autoimmunity
Tian L,De Hertogh G,Fedeli M,Staats KA,Schonefeldt S,Humblet-Baron S,Van Den Bosch L,Dellabona P,Dooley J,Liston A
25-7311 was used in Flow cytometry/Cell sorting to elucidate the dominant effects of the T cell microRNA expression network and explore it as a potential therapeutic target for autoimmune diseases.
Wed Feb 01 00:00:00 UTC 2012
Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders.
Journal of virology
Seedhom MO,Mathurin KS,Kim SK,Welsh RM
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jun 01 00:00:00 UTC 2012
Treatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells.
Cancer gene therapy
Gao Y,Whitaker-Dowling P,Griffin JA,Bergman I
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Sun Apr 01 00:00:00 UTC 2012
IL-10 limits parasite burden and protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.
Journal of immunology (Baltimore, Md. : 1950)
Roffê E,Rothfuchs AG,Santiago HC,Marino AP,Ribeiro-Gomes FL,Eckhaus M,Antonelli LR,Murphy PM
25-7311 was used in Flow cytometry/Cell sorting to investigate the mechanism by which IL-10 protects against fatal myocarditis in a mouse model of Trypanosoma cruzi infection.
Sun Jan 15 00:00:00 UTC 2012
Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Oh S,Aitken M,Simons DM,Basehoar A,Garcia V,Kropf E,Caton AJ
25-7311 was used in Flow cytometry/Cell sorting to investigate why CD4(+)CD25(+)Foxp3(+) Tregs allow organ-specific autoimmunity, showing that polyclonal Tregs suppressed Th17 cell formation and prevented arthritis development, but clonotypic Tregs did not, indicating that diverse TCR specificities are required.
Tue May 01 00:00:00 UTC 2012
Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen.
Journal of immunology (Baltimore, Md. : 1950)
Hayashi C,Papadopoulos G,Gudino CV,Weinberg EO,Barth KR,Madrigal AG,Chen Y,Ning H,LaValley M,Gibson FC,Hamilton JA,Genco CA
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Tue Feb 14 00:00:00 UTC 2012
Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset.
Infection and immunity
Lindenstrøm T,Woodworth J,Dietrich J,Aagaard C,Andersen P,Agger EM
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that subunit vaccination in mice with CAF01 leads to establishment of bona fide Th17 memory cells.
Mon Oct 01 00:00:00 UTC 2012
Failure to recruit anti-inflammatory CD103+ dendritic cells and a diminished CD4+ Foxp3+ regulatory T cell pool in mice that display excessive lung inflammation and increased susceptibility to Mycobacterium tuberculosis.
Infection and immunity
Leepiyasakulchai C,Ignatowicz L,Pawlowski A,Källenius G,Sköld M
25-7311 was used in Immunocytochemistry to increase our understanding of mechanisms that may regulate the host immune response in M. tuberculosis-infected lungs.
Thu Mar 01 00:00:00 UTC 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using IFN gamma monoclonal antibody (Product # 25-7311-41) in Flow Cytometry
Fri Jul 19 00:00:00 UTC 2013
Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.
Blood
Tian L,Altin JA,Makaroff LE,Franckaert D,Cook MC,Goodnow CC,Dooley J,Liston A
25-7311 was used in Immunocytochemistry to demonstrate that Th2-driven diseases may be more responsive to regulatory T-cell manipulation.
Thu Aug 18 00:00:00 UTC 2011
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
25-7311 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 UTC 2011
Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization.
Journal of immunology (Baltimore, Md. : 1950)
Schmidt NW,Harty JT
25-7311 was used in Flow cytometry/Cell sorting to investigate whether unrelated infections will compromise numbers of Plasmodium-specific memory CD8 T cells, showing that attrition of Plasmodium-specific cells is rescued by booster immunisation.
Fri Apr 01 00:00:00 UTC 2011
CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites.
PloS one
Overstreet MG,Chen YC,Cockburn IA,Tse SW,Zavala F
25-7311 was used in Flow cytometry/Cell sorting to investigate CD4+ T cells modulation of effector and memory CD8+ T cells, induced by malaria sporozoites.
Tue Jan 04 00:00:00 UTC 2011
Antigen aggregation decides the fate of the allergic immune response.
Journal of immunology (Baltimore, Md. : 1950)
Zaborsky N,Brunner M,Wallner M,Himly M,Karl T,Schwarzenbacher R,Ferreira F,Achatz G
25-7311 was used in Flow cytometry/Cell sorting to elucidate the molecular background of hypoallergenicity using Betula verrucosa.
Fri Jan 15 00:00:00 UTC 2010
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lindenstrøm T,Agger EM,Korsholm KS,Darrah PA,Aagaard C,Seder RA,Rosenkrands I,Andersen P
25-7311 was used in Flow cytometry/Cell sorting to demonstrate that adjuvanted subunit vaccines can promote long-term protective immune responses characterized by high levels of persisting multifunctional T cells.
Mon Jun 15 00:00:00 UTC 2009
T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells.
Blood
Matsuda JL,Zhang Q,Ndonye R,Richardson SK,Howell AR,Gapin L
25-7311 was used in Flow cytometry/Cell sorting to identify some of the genetic targets of T-bet during V14i NKT-cell lineage development.
Sat Apr 01 00:00:00 UTC 2006
