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Recommended positive control is mouse spleen.
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
蛋白别名: class II cytokine receptor 12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda R1; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Interferon lambda receptor 1; interferon-lambda receptor 1; interleukin 28 receptor alpha; Interleukin-28; Interleukin-28 receptor subunit alpha
基因别名: CRF2-12; Ifnlr1; Il28ra; RGD1562689
UniProt ID: (Mouse) Q8CGK5
分子生物学功能: transmembrane signal receptor