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Proteintech
IFRG15 Polyclonal Antibody
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产品信息
21825-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IFRG15 Fusion Protein Ag16156 (1-131 aa encoded by BC098348)
偶联物
形式
Liquid
浓度
0.67 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MFSDNSHCP DCGQQWFPSL ELGHWLYQTE LVENECYQVF LDRINRADYC PECYPDNPAN RSLVLPWSFP LEWAPQNLTR WTFEKACHPF LLGPPLVRKR IHDSRVAGFN PALQLILTRT DKTLNKKLGQ NK (1-131 aa encoded by BC098348)
靶标信息
Torsin-1A-interacting protein 2, isoform IFRG15, also known as TOR1AIP2 or LULL1, is a protein encoded by the TOR1AIP2 gene, existing in different forms (isoforms) due to alternative splicing, with IFRG15 being an interferon-responsive one, while the main form (isoform b) is an integral ER membrane protein that regulates the ATPase TorsinA, crucial for early-onset dystonia if defective. This protein acts as a cofactor for TorsinA, influencing its localization and activity, and plays roles in the endoplasmic reticulum/nuclear envelope dynamics and potentially in odontogenesis (tooth development) and craniofacial development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 15 kDa interferon-responsive protein; IFRG15; interferon responsive gene 15; lumenal domain like LAP1; Lumenal domain-like LAP1; torsin A interacting protein 2; Torsin-1A-interacting protein 2; Torsin-1A-interacting protein 2, isoform IFRG15
基因别名: IFRG15; LULL1; NET9; TOR1AIP2
UniProt ID: (Human) Q9H496
Entrez Gene ID: (Human) 163590
