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Proteintech
IFT122 Polyclonal Antibody
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产品信息
19304-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IFT122 Fusion Protein Ag6860 (1-359 aa encoded by BC004238)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MRAVLTWRD KAEHCINDIA FKPDGTQLIL AAGSRLLVYD TSDGTLLQPL KGHKDTVYCV AYAKDGLWSP EQKSVSKHKS SSKIICCSWT NDGQYLALGM FNGIISIRNK NGEEKVKIER PGGSLSPIWS ICWNPSREER NDILAVADWG QKVSFYQLSG KQIGKDRALN FDPCCISYFT KGEYILLGGS DKQVSLFTKD GVRLGTVGEQ NSWVWTCQAK PDSNYVVVGC QDGTISFYQL IFSTVHGLYK DRYAYRDSMT DVIVQHLITE QKVRIKCKEL VKKIAIYRNR LAIQLPEKIL IYELYSEDLS DMHYRVKEKI IKKFECNLLV VCANHIILCQ EKRLQCLSFS GVKEREWQME (1-359 aa encoded by BC004238)
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: intraflagellar transport 122 homolog; Intraflagellar transport protein 122 homolog; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140
基因别名: C86139; CED; CED1; IFT122; sopb; SPG; WDR10; WDR10p; WDR140
UniProt ID: (Human) Q9HBG6, (Mouse) Q6NWV3
Entrez Gene ID: (Human) 55764, (Mouse) 81896
neural tube closure
signal transduction downstream of smoothened
multicellular organism development
dorsal/ventral pattern formation
embryonic body morphogenesis
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
cell projection organization
embryonic heart tube development
embryonic forelimb morphogenesis
intraciliary anterograde transport
intraciliary retrograde transport
cilium assembly
embryonic digit morphogenesis
negative regulation of smoothened signaling pathway
camera-type eye morphogenesis
negative regulation of epithelial cell proliferation
limb development
cilium morphogenesis
ciliary receptor clustering involved in smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
embryonic heart tube left/right pattern formation
protein localization to cilium
establishment of protein localization to organelle
intraciliary transport involved in cilium morphogenesis
