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Invitrogen
IFT172 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-25305
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human IFT172
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with rat based on sequence homology.
靶标信息
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: intraflagellar transport 172 homolog; intraflagellar transport 172 protein; protein wimple; selective LIM binding factor homolog; selective LIM-binding factor Wimple; unnamed protein product; wimple homolog
基因别名: 4930553F24Rik; avc1; BBS20; NPHP17; osm-1; RP71; SLB; SRTD10; wim
UniProt ID: (Human) Q9UG01, (Mouse) Q6VH22
Entrez Gene ID: (Human) 26160, (Mouse) 67661
negative regulation of transcription from RNA polymerase II promoter
neural tube formation
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
determination of left/right symmetry
brain development
heart development
epidermis development
regulation of smoothened signaling pathway
dorsal/ventral pattern formation
protein processing
spinal cord motor neuron differentiation
neural tube development
cytoplasmic microtubule organization
intraciliary anterograde transport
intraciliary transport
positive regulation of smoothened signaling pathway
negative regulation of epithelial cell proliferation
palate development
limb development
cilium morphogenesis
bone development
hindgut development
left/right axis specification
non-motile cilium assembly
cilium organization
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