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Invitrogen
IFT172 Polyclonal Antibody
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产品信息
PA5-60861
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SSPGTNCAEA YHSWADLRDV LFNLCENLVK SSEANSPAHE EFKTMLLIAH YYATRSAAQS VKQLETVAAR LSVSLLRHTQ LLPVDKAFYE AGIAAKAVGW DNMAFIFLNR
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
靶标信息
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: intraflagellar transport 172 homolog; Intraflagellar transport protein 172 homolog; selective LIM binding factor homolog; wimple homolog
基因别名: BBS20; IFT172; KIAA1179; NPHP17; osm-1; RP71; SLB; SRTD10; wim
UniProt ID: (Human) Q9UG01
Entrez Gene ID: (Human) 26160
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
brain development
epidermis development
dorsal/ventral pattern formation
protein processing
spinal cord motor neuron differentiation
cytoplasmic microtubule organization
cilium assembly
positive regulation of smoothened signaling pathway
negative regulation of epithelial cell proliferation
palate development
limb development
bone development
hindgut development
left/right axis specification
