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Abnova
IFT74 Monoclonal Antibody (2B6)
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产品信息
H00080173-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B6
抗原
IFT74 (NP_079379, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MEEVMNGYNM LKAQNDRETQ SLDVIFTERQ AKEKQIRSVE EEIEQEKQAT DDIIKNMSLE NQVKYLEMKT TNEKLLQELD TLQQQLDSQN MKKESLEAEI
靶标信息
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Capillary morphogenesis gene 1 protein; capillary morphogenesis protein 1; CMG-1; coiled-coil domain containing 2; Coiled-coil domain-containing protein 2; intraflagellar transport 74 homolog; Intraflagellar transport protein 74 homolog
基因别名: CCDC2; CMG-1; CMG1; IFT74
UniProt ID: (Human) Q96LB3
Entrez Gene ID: (Human) 80173
keratinocyte development
Notch signaling pathway
determination of left/right symmetry
heart development
positive regulation of cell adhesion mediated by integrin
intraciliary transport involved in cilium morphogenesis
cilium assembly
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
