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Invitrogen
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MA5-13802 targets IGF-1 Receptor alpha in ELISA, IHC, ICC/IF and IP applications and shows reactivity with human samples. Does not react with rat.
The MA5-13802 immunogen is iGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA, epitope aa 283-440.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。