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Proteintech
IGF2BP2 Polyclonal Antibody
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产品信息
11601-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IGF2BP2 Fusion Protein Ag2142 (1-341 aa encoded by BC021290)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody raise against part of N-terminus of human IGF2BP2.
Immunogen sequence: MNKLYIGNL SPAVTADDLR QLFGDRKLPL AGQVLLKSGY AFVDYPDQNW AIRAIETLSG KVELHGKIME VDYSVSKKLR SRKIQIRNIP PHLQWEVLDG LLAQYGTVEN VEQVNTDTET AVVNVTYATR EEAKIAMEKL SGHQFENYSF KISYIPDEEV SSPSPPQRAQ RGDHSSREQG HAPGGTSQAR QIDFPLRILV PTQFVGAIIG KEGLTIKNIT KQTQSRVDIH RKENSGAAEK PVTIHATPEG TSEACRMILE IMQKEADETK LAEEIPLKIL AHNGLVGRLI GKEGRNLKKI EHETGTKITI SSLQDLSIYN PERTITVKGT VEACASAEIE IM (1-341 aa encoded by BC021290)
靶标信息
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; Insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; p62; VICKZ family member 2
基因别名: C330012H03Rik; IGF2BP2; IMP-2; IMP2; Neilsen; RGD1305614; VICKZ2
UniProt ID: (Human) Q9Y6M1, (Mouse) Q5SF07
Entrez Gene ID: (Human) 10644, (Mouse) 319765, (Rat) 303824
