Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
IGFBP2 Antibody (711228) in WB
Western blot analysis was performed on Whole cell extracts (30 µg lysate) of T-47D (Lane 1), T-47D (Condition Media) (Lane 2), PC-3 (Lane 3), PC-3 (Condition Media) (Lane 4), HeLa (Lane 5), HeLa (Condition Media) (Lane 6), SH-SY5Y (Lane 7), SH-SY5Y (Condition Media) (Lane 8). The blots were probed with Anti-IGFBP2 Recombinant Rabbit Polyclonal Antibody (Product # 711228, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 di... View More
产品信息
711228
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
1HCLC
抗原
Protein corresponding to Human IGFBP2 (aa 130-325)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633136
产品详细信息
This antibody is predicted to react with Monkey, Bovine, Pig, Sheep and Goat
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
靶标信息
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; Insulin like growth factor binding protein; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; Insulin-like growth factor-binding protein 2; OTTHUMP00000207753
基因别名: BP2; IBP2; IGF-BP53; IGFBP2
UniProt ID: (Human) P18065
Entrez Gene ID: (Human) 3485
regulation of cell growth
signal transduction
female pregnancy
aging
response to nutrient
response to mechanical stimulus
response to lithium ion
response to estradiol
response to retinoic acid
cellular response to hormone stimulus
positive regulation of activated T cell proliferation
response to drug
regulation of insulin-like growth factor receptor signaling pathway
response to estrogen
cellular protein metabolic process
response to glucocorticoid
negative regulation of canonical Wnt signaling pathway
