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Proteintech
IGSF3 Polyclonal Antibody
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产品信息
18072-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IGSF3 fusion protein Ag12711
偶联物
形式
Liquid
浓度
750 µg/mL
规格
112.5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: QVTVQEGPLY RTEGSHITIW CNVSGYQGPS EQNFQWSIYL PSSPEREVQI VSTMDSSFPY AIYTQRVRGG KIFIERVQGN STLLHITDLQ ARDAGEYECH TPSTDKQYFG SYSAKMNLVV IPDSLQTTAM PQTLHRVEQD PLELTCEVAS ETIQHSHLSV AWLRQKVGEK PVEVISLSRD FMLHSSSEYA QRQSLGEVRL DKLGRTTFRL TIFHLQPSDQ GEFYCEAAEW IQDPDGSWYA MTRKRSEGAV VNVQPTDKEF TVRLETEKRL HTVGEPVEFR CILEAQNVPD RYFAVSWAFN SSLIATMGPN AVPVLNSEFA HREARGQLKV A
靶标信息
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; IgSF3; immunoglobin superfamily, member 3; Immunoglobulin superfamily member 3; RP4-781D12.1; unnamed protein product
基因别名: EWI-3; EWI3; IGSF3; KIAA0466; LCDD; V8
UniProt ID: (Human) O75054
Entrez Gene ID: (Human) 3321
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