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Invitrogen
IGSF5 Polyclonal Antibody
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产品信息
PA5-47542
产品规格
种属反应
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse JAM-4/IGSF5 Leu15-Ala139
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) JAM-A, rmJAM-B, and rmJAM-C is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell adhesion molecule JCAM; IgSF5; Immunoglobulin superfamily member 5; JAM-4; junction adhesion molecule 4; Junctional adhesion molecule 4
基因别名: 2010003D20Rik; Igsf5; Jam4; JCAM
UniProt ID: (Mouse) Q7TSN7
Entrez Gene ID: (Mouse) 72058
