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Invitrogen
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PA1-25721 detects IKK alpha from human, mouse, and rat samples.
PA1-25721 has been successfully used in Western blot procedures.
The PA1-25721 immunogen is a synthetic peptide corresponding to residues 311-377 of human IKK alpha.
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。