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Proteintech
IKZF1 Polyclonal Antibody
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产品信息
12016-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IKZF1 Fusion Protein Ag2631 (1-303 aa encoded by BC018349)
偶联物
形式
Liquid
浓度
0.27 mg/mL
规格
40.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDADEGQDM SQVSGKESPP VSDTPDEGDE PMPIPEDLST TSGGQQSSKS DRVVASNVKV ETQSDEENGR ACEMNGEECA EDLRMLDASG EKMNGSHRDQ GSSALSGVGG IRLPNGKLKC DICGIICIGP NVLMVHKRSH TGERPFQCNQ CGASFTQKGN LLRHIKLHSG EKPFKCHLCN YACRRRDALT GHLRTHSVIK EETNHSEMAE DLCKIGSERS LVLDRLASNV AKRKSSMPQK FLGDKGLSDT PYDSSASYEK ENEMMKSHVM DQAINNAINY LGAESLRPLV QTPPGGSEVV PVIS (1-303 aa encoded by BC018349)
靶标信息
DNA-binding protein IKAROS functions in the specification and the maturation of the T lymphocyte. It also interacts with a critical control element in the terminal deoxynucleotidyl transferase promoter as well as with the promoters for other genes expressed during early stages of B-cell and T-cell development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CLL-associated antigen KW-6; DNA-binding protein Ikaros; hIk-1; Ikaros family zinc finger protein 1; Ikaros zinc finger protein; zinc finger protein subfamily 1A 1; DNA-binding protein Ikaros; CLL-associated antigen KW-6; Ikaros family zinc finger protein 1; lymphoid transcription factor LyF-1; lymphocyte-restricted zinc finger DNA binding protein; Lymphoid transcription factor LyF-1; predicted protein of HQ0758; protein phosphatase 1, regulatory subunit 92; unnamed protein product; zinc finger protein, subfamily 1A, 1 (Ikaros); zinc finger transcription factor
基因别名: 5832432G11Rik; CVID13; hlk-1; Hs.54452; IK1; IKAROS; IKZF1; LyF-1; LYF1; mKIAA4227; PPP1R92; PRO0758; RGD1562979; Zfpn1a1; ZNFN1A1
UniProt ID: (Human) Q13422
Entrez Gene ID: (Human) 10320, (Mouse) 22778, (Rat) 305501
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
protein domain specific binding
identical protein binding
metal ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
C2H2 zinc finger transcription factor
chromatin organization
regulation of transcription from RNA polymerase II promoter
mesoderm development
lymphocyte differentiation
erythrocyte differentiation
negative regulation of transcription, DNA-templated
negative regulation of transcription from RNA polymerase II promoter
natural killer cell differentiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
hemopoiesis
B cell differentiation
T cell differentiation
forebrain development
positive regulation of multicellular organism growth
positive regulation of B cell differentiation
positive regulation of neutrophil differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lymph node development
thymus development
Peyer's patch development
gland development
positive regulation of NK T cell differentiation
retina development in camera-type eye
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