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Proteintech
IL-16 Monoclonal Antibody (1C4C7)
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产品信息
66145-1-IG
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
1C4C7
抗原
IL-16 Fusion Protein Ag16466 (154-454 aa encoded by BC040272)
偶联物
形式
Liquid
浓度
1.52 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTKKSAAPT DRQPYSLCSN RKSLSQQLDC PAGKAAGTSR PTRSLSTAQL VQPSGGLQAS VISNIVLMKG QAKGLGFSIV GGKDSIYGPI GIYVKTIFAG GAAAADGRLQ EGDEILELNG ESMAGLTHQD ALQKFKQAKK GLLTLTVRTR LTAPPSLCSH LSPPLCRSLS SSTCITKDSS SFALESPSAP ISTAKPNYRI MVEVSLQKEA GVGLGIGLCS VPYFQCISGI FVHTLSPGSV AHLDGRLRCG DEIVEISDSP VHCLTLNEVY TILSHCDPGP VSIIVSRHPD PQKEEMEAQE VK (154-454 aa encoded by BC040272)
靶标信息
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; ILN; Interleukin; Interleukin16; lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
基因别名: IL16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603
