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Invitrogen
IL-34 Polyclonal Antibody
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IL-34 Antibody (PA5-95624) in IHC (P)
Immunohistochemistry analysis of IL-34 in paraffin-embedded mouse spleen tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with IL-34 polyclonal antibody (Product # PA5-95624) at a 1 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavidin-Biotin-Complex and DAB... View More
产品信息
PA5-95624
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human Interleukin 34/IL34 (NEPLEMWPLTQNEECTVTGFLRDKLQYR).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whle cell, human A549 whole cell, human SH-SY5Y whole cell, human U87 whole cell, human CACO-2 whole cell, human U20S whole cell, human HEK293 whole cell, rat C6 whole cell,mouse ANA-1 whole cell. IHC: mhuman liver cancer tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: IL-34; ILN; Interleukin; Interleukin-34; Interleukin34
基因别名: 2010004A03Rik; AI593503; C16orf77; IL-34; IL34
UniProt ID: (Human) Q6ZMJ4, (Mouse) Q8R1R4, (Rat) Q4KM46
Entrez Gene ID: (Human) 146433, (Mouse) 76527, (Rat) 498951
