应用 | 建议稀释比 | 已发表文章 |
---|---|---|
酶联免疫吸附实验 (ELISA) |
Assay-dependent | 查看1篇已发表文章 1篇已发表文章 |
产品规格 | |
---|---|
种属反应 |
Human |
已发表种属 |
Human |
宿主/亚型 |
Mouse / IgG1, kappa |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
860F10H12 |
抗原 |
Purified human recombinant IL-4. |
偶联物 |
Biotin |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS, pH 7.5, with 5mg/mL BSA |
内含物 |
0.05% sodium azide |
保存条件 |
4° C |
RRID |
AB_2536258 |
This product is recommended as a detection antibody in Sandwich ELISA applications.
This clone can also be referred to as clone number 860F 10H12 4E2.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B cell growth factor 1; B-cell stimulatory factor 1; B_cell stimulatory factor 1; Binetrakin; BSF-1; H-IL-4; IL-4; ILN; Interleukin; interleukin 4 variant 2; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402; Pitrakinra
基因别名: BCGF-1; BCGF1; BSF-1; BSF1; IL-4; IL4
UniProt ID: (Human) P05112
Entrez Gene ID: (Human) 3565
分子生物学功能:
interleukin superfamily