Product References
Zika Virus Infection Induces Interleukin-1β-Mediated Inflammatory Responses by Macrophages in the Brain of an Adult Mouse Model.
Journal of virology
Jeong GU,Lee S,Kim DY,Lyu J,Yoon GY,Kim KD,Ku KB,Ko J,Kwon YC
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Flow Cytometry
Thu Jun 29 00:00:00 UTC 2023
SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1.
Journal of cell communication and signaling
Olou AA,Ambrose J,Jack JL,Walsh M,Ruckert MT,Eades AE,Bye BA,Dandawate P,VanSaun MN
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Neutralization
Fri Sep 01 00:00:00 UTC 2023
A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice.
Molecular metabolism
Long F,Bhatti MR,Kellenberger A,Sun W,Modica S,Höring M,Liebisch G,Krieger JP,Wolfrum C,Challa TD
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Neutralization
Wed Mar 01 00:00:00 UTC 2023
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Flow Cytometry
Wed Feb 16 00:00:00 UTC 2022
Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis.
Journal of neuroinflammation
Chen D,Jia G,Zhang Y,Mao H,Zhao L,Li W,Chen Y,Ni Y
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunocytochemistry
Mon Feb 28 00:00:00 UTC 2022
Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis.
Journal of neuroinflammation
Chen D,Jia G,Zhang Y,Mao H,Zhao L,Li W,Chen Y,Ni Y
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunocytochemistry
Mon Feb 28 00:00:00 UTC 2022
Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis.
Journal of neuroinflammation
Chen D,Jia G,Zhang Y,Mao H,Zhao L,Li W,Chen Y,Ni Y
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunocytochemistry
Mon Feb 28 00:00:00 UTC 2022
Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response.
International journal of molecular sciences
Milosevic K,Stevanovic I,Bozic ID,Milosevic A,Janjic MM,Laketa D,Bjelobaba I,Lavrnja I,Savic D
14-7061-81 was used in ELISA to show that agmatine suppresses nitrosative and oxidative burst in Lps-stimulated microglia by reducing iNOS and XO activity and decreasing O2- levels, arresting lipid peroxidation, increasing total glutathione content, and preserving GR and CAT activity.
Thu Mar 24 00:00:00 UTC 2022
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Immunity
Xian H,Liu Y,Rundberg Nilsson A,Gatchalian R,Crother TR,Tourtellotte WG,Zhang Y,Aleman-Muench GR,Lewis G,Chen W,Kang S,Luevanos M,Trudler D,Lipton SA,Soroosh P,Teijaro J,de la Torre JC,Arditi M,Karin M,Sanchez-Lopez E
14-7061-81 was used in ELISA to conclude that inhibition of ATP and mtDNA synthesis is sufficient for ARDS amelioration.
Tue Jul 13 00:00:00 UTC 2021
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Immunity
Xian H,Liu Y,Rundberg Nilsson A,Gatchalian R,Crother TR,Tourtellotte WG,Zhang Y,Aleman-Muench GR,Lewis G,Chen W,Kang S,Luevanos M,Trudler D,Lipton SA,Soroosh P,Teijaro J,de la Torre JC,Arditi M,Karin M,Sanchez-Lopez E
14-7061-81 was used in ELISA to conclude that inhibition of ATP and mtDNA synthesis is sufficient for ARDS amelioration.
Tue Jul 13 00:00:00 UTC 2021
Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia.
The Journal of experimental medicine
Rupert JE,Narasimhan A,Jengelley DHA,Jiang Y,Liu J,Au E,Silverman LM,Sandusky G,Bonetto A,Cao S,Lu X,O'Connell TM,Liu Y,Koniaris LG,Zimmers TA
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Neutralization
Mon Jun 07 00:00:00 UTC 2021
Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE-/- mice fed high fat diet.
Journal of biomedical science
Lee GL,Liao TL,Wu JY,Wu KK,Kuo CC
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in ELISA
Mon Nov 08 00:00:00 UTC 2021
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Oxidative medicine and cellular longevity
Luo Y,Guo J,Jia W,Wu M,Yin F,Niu G,Shih DQ,Targan SR,Zhang X
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Flow Cytometry
Fri Mar 04 00:00:00 UTC 2022
Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies.
Frontiers in cellular and infection microbiology
Alford MA,Choi KG,Trimble MJ,Masoudi H,Kalsi P,Pletzer D,Hancock REW
14-7061 was used in an ELISA assay to describe a simple less virulent, epidemic P. aeruginosa cystic fibrosis clinical isolate LESB65 model allowing non-invasive tracking of bacterial infection, and screening of host-responses to infection and therapies.
Fri Jul 02 00:00:00 UTC 2021
Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies.
Frontiers in cellular and infection microbiology
Alford MA,Choi KG,Trimble MJ,Masoudi H,Kalsi P,Pletzer D,Hancock REW
14-7061 was used in an ELISA assay to describe a simple less virulent, epidemic P. aeruginosa cystic fibrosis clinical isolate LESB65 model allowing non-invasive tracking of bacterial infection, and screening of host-responses to infection and therapies.
Fri Jul 02 00:00:00 UTC 2021
Betulinic Acid Ameliorates the Severity of Acute Pancreatitis via Inhibition of the NF-κB Signaling Pathway in Mice.
International journal of molecular sciences
Zhou Z,Choi JW,Shin JY,Kim DU,Kweon B,Oh H,Kim YC,Song HJ,Bae GS,Park SJ
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunocytochemistry
Sat Jun 26 00:00:00 UTC 2021
Origin and Function of Stress-Induced IL-6 in Murine Models.
Cell
Qing H,Desrouleaux R,Israni-Winger K,Mineur YS,Fogelman N,Zhang C,Rashed S,Palm NW,Sinha R,Picciotto MR,Perry RJ,Wang A
14-7061-81 was used in Immunohistochemistry to study the cytokine interleukin-6 (IL-6) and its induction following acute stress in mouse models.
Thu Jul 23 00:00:00 UTC 2020
Origin and Function of Stress-Induced IL-6 in Murine Models.
Cell
Qing H,Desrouleaux R,Israni-Winger K,Mineur YS,Fogelman N,Zhang C,Rashed S,Palm NW,Sinha R,Picciotto MR,Perry RJ,Wang A
14-7061-81 was used in Immunohistochemistry to study the cytokine interleukin-6 (IL-6) and its induction following acute stress in mouse models.
Thu Jul 23 00:00:00 UTC 2020
Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.
Mucosal immunology
Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunohistochemistry
Wed Jul 01 00:00:00 UTC 2020
Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.
Mucosal immunology
Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Immunohistochemistry
Wed Jul 01 00:00:00 UTC 2020
Differential Activation of Macrophages Based on Their Environment in Advanced Age.
Chonnam medical journal
Lee DY,Lim JS,Cho KA
14-7061-81 was used in ELISA to describe the differential activity of peritoneal macrophages with or without the presence of thioglycollate, an inflammatory drug that encouraged the recruitment of macrophages, during aging.
Wed Jan 01 00:00:00 UTC 2020
Differential Activation of Macrophages Based on Their Environment in Advanced Age.
Chonnam medical journal
Lee DY,Lim JS,Cho KA
14-7061-81 was used in ELISA to describe the differential activity of peritoneal macrophages with or without the presence of thioglycollate, an inflammatory drug that encouraged the recruitment of macrophages, during aging.
Wed Jan 01 00:00:00 UTC 2020
Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation.
Brain sciences
Thome R,Boehm A,Ishikawa LLW,Casella G,Munhoz J,Ciric B,Zhang GX,Rostami A
14-7061-81 was used in Flow Cytometry to analyse the CNS of experimental autoimmune encephalomyelitis mice to identify and characterize the cells that are affected by chloroquine.
Fri Jun 05 00:00:00 UTC 2020
GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance.
Cell
Luan HH,Wang A,Hilliard BK,Carvalho F,Rosen CE,Ahasic AM,Herzog EL,Kang I,Pisani MA,Yu S,Zhang C,Ring AM,Young LH,Medzhitov R
14-7061 was used in an ELISA assay to show that GDF15 coordinates tolerance to inflammatory damage through regulation of triglyceride metabolism.
Thu Aug 22 00:00:00 UTC 2019
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Cell metabolism
Sanchez-Lopez E,Zhong Z,Stubelius A,Sweeney SR,Booshehri LM,Antonucci L,Liu-Bryan R,Lodi A,Terkeltaub R,Lacal JC,Murphy AN,Hoffman HM,Tiziani S,Guma M,Karin M
14-7061 was used in Western Blotting to conclude that choline kinase inhibitors ameliorated acute and chronic models of IL-1β-dependent inflammation.
Tue Jun 04 00:00:00 UTC 2019
TLR2 Promotes Vascular Smooth Muscle Cell Chondrogenic Differentiation and Consequent Calcification via the Concerted Actions of Osteoprotegerin Suppression and IL-6-Mediated RANKL Induction.
Arteriosclerosis, thrombosis, and vascular biology
Lee GL,Yeh CC,Wu JY,Lin HC,Wang YF,Kuo YY,Hsieh YT,Hsu YJ,Kuo CC
14-7061-81 was used in ELISA to study the role of Toll-like receptor 2 in vascular calcification during atherosclerosis.
Fri Mar 01 00:00:00 UTC 2019
Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation.
Scientific reports
Dai D,Yuan J,Wang Y,Xu J,Mao C,Xiao Y
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in ELISA
Wed May 29 00:00:00 UTC 2019
Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production.
International journal of molecular sciences
Yeh CC,Wu JY,Lee GL,Wen HT,Lin P,Kuo CC
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in ELISA
Wed Dec 04 00:00:00 UTC 2019
Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production.
International journal of molecular sciences
Yeh CC,Wu JY,Lee GL,Wen HT,Lin P,Kuo CC
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in ELISA
Wed Dec 04 00:00:00 UTC 2019
Serum developmental endothelial locus-1 is associated with severity of sepsis in animals and humans.
Scientific reports
Kim WY,Lee SH,Kim DY,Ryu HJ,Chon GR,Park YY,Fu Y,Huh JW,Lim CM,Koh Y,Choi EY,Hong SB
14-7061-81 was used in ELISA to hypothesize that degradation of the endothelial glycocalyx during sepsis may increase serum Del-1.
Tue Sep 10 00:00:00 UTC 2019
Absence of GdX/UBL4A Protects against Inflammatory Diseases by Regulating NF-кB Signaling in Macrophages and Dendritic Cells.
Theranostics
Liu C,Zhou Y,Li M,Wang Y,Yang L,Yang S,Feng Y,Wang Y,Wang Y,Ren F,Li J,Dong Z,Chin YE,Fu X,Wu L,Chang Z
14-7061-81 was used in ELISA to investigate whether ubiquitin-like protein 4A has a role during the innate immune response.
Fri Jan 31 00:00:00 UTC 2020
Frontline Science: Proliferation of Ly6C+ monocytes during urinary tract infections is regulated by IL-6 trans-signaling.
Journal of leukocyte biology
Dixit A,Bottek J,Beerlage AL,Schuettpelz J,Thiebes S,Brenzel A,Garbers C,Rose-John S,Mittrücker HW,Squire A,Engel DR
14-7061 was used in Blocking experiments to analyse the proliferative capacity of Ly6C+ monocytes in the urinary bladder after infection with uropathogenic Escherichia coli.
Mon Jan 01 00:00:00 UTC 2018
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
JCI insight
Wasnik S,Rundle CH,Baylink DJ,Yazdi MS,Carreon EE,Xu Y,Qin X,Lau KW,Tang X
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Flow Cytometry
Thu Sep 06 00:00:00 UTC 2018
Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues.
Oncotarget
Muccioli M,Nandigam H,Loftus T,Singh M,Venkatesh A,Wright J,Pate M,McCall K,Benencia F
14-7061 was used in an ELISA assay to investigate the potential of mouse and human ovarian cancer cells to produce inflammatory factors in response to pathogen recognition receptor signalling.
Fri Nov 30 00:00:00 UTC 2018
Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.
Cell host & microbe
Maruzuru Y,Ichinohe T,Sato R,Miyake K,Okano T,Suzuki T,Koshiba T,Koyanagi N,Tsuda S,Watanabe M,Arii J,Kato A,Kawaguchi Y
14-7061-81 was used in ELISA to reveal a mechanism of HSV-1 evasion of the host immune response that enables efficient viral replication in vivo.
Wed Feb 14 00:00:00 UTC 2018
Increased cathepsin S in Prdm1-/- dendritic cells alters the TFH cell repertoire and contributes to lupus.
Nature immunology
Kim SJ,Schätzle S,Ahmed SS,Haap W,Jang SH,Gregersen PK,Georgiou G,Diamond B
14-7061-81 was used in Western Blot to explore the repertoire of follicular helper T cells in patients with lupus.
Fri Sep 01 00:00:00 UTC 2017
Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.
The Journal of pathology
Sheng L,Jena PK,Hu Y,Liu HX,Nagar N,Kalanetra KM,French SW,French SW,Mills DA,Wan YY
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Western Blot
Fri Dec 01 00:00:00 UTC 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-7061-81 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 UTC 2017
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Flow Cytometry
Thu Jun 01 00:00:00 UTC 2017
IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity.
Journal of immunology (Baltimore, Md. : 1950)
Braune J,Weyer U,Hobusch C,Mauer J,Brüning JC,Bechmann I,Gericke M
14-7061 was used in functional assays to study how IL-6 acts as a Th2 cytokine in obesity by stimulating M2 polarisation and local adipose tissue macrophages proliferation.
Sat Apr 01 00:00:00 UTC 2017
Vitamin A differentially regulates cytokine expression in respiratory epithelial and macrophage cell lines.
Cytokine
Penkert RR,Jones BG,Häcker H,Partridge JF,Hurwitz JL
14-7061 was used in an ELISA assay to evaluate the cell specific effects of retinoic acid on PAMP triggered cytokine expression for LETs and macrophages in mice.
Wed Mar 01 00:00:00 UTC 2017
Orally administered sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice.
Experimental and therapeutic medicine
Ono K,Nimura S,Hideshima Y,Nabeshima K,Nakashima M
14-7061 was used in an ELISA assay to investigate the effects of orally administered sodium 4-phenylbutyrate in mice.
Fri Dec 01 00:00:00 UTC 2017
Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle.
Cell stem cell
Chiche A,Le Roux I,von Joest M,Sakai H,Aguín SB,Cazin C,Salam R,Fiette L,Alegria O,Flamant P,Tajbakhsh S,Li H
14-7061 was used in Functional assays to study the effects of acute and chronic injury on transcription-factor-mediated reprogramming in skeletal muscle.
Thu Mar 02 00:00:00 UTC 2017
Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation.
Cell
Wang A,Huen SC,Luan HH,Yu S,Zhang C,Gallezot JD,Booth CJ,Medzhitov R
14-7061 was used in an ELISA assay to analyse the effects of anorxia in mouse models wih viral and bacterial infections.
Thu Sep 08 00:00:00 UTC 2016
K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.
Cell death and differentiation
Shutinoski B,Alturki NA,Rijal D,Bertin J,Gough PJ,Schlossmacher MG,Sad S
14-7061 was used in an ELISA assay to investigate the impact of a K45A mutation of RIPK1 on necroptosis of macrophages and the activation of inflammatory response.
Sat Oct 01 00:00:00 UTC 2016
Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
International journal of cancer
Ray AL,Castillo EF,Morris KT,Nofchissey RA,Weston LL,Samedi VG,Hanson JA,Gaestel M,Pinchuk IV,Beswick EJ
14-7061-81 was used in Flow Cytometry to investigate the role of MAPK-activated protein kinase 2 in development of colitis-associated colon cancer.
Mon Feb 01 00:00:00 UTC 2016
Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation.
Scientific reports
Takagi H,Arimura K,Uto T,Fukaya T,Nakamura T,Choijookhuu N,Hishikawa Y,Sato K
14-7061 was used in Functional assays to investigate the role of plasmacytoid dendritic cells in autoimmunity, showing that they orchestrate TLR7-mediated immune response and initiate autoimmune inflammation.
Thu Apr 14 00:00:00 UTC 2016
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.
Nature communications
Ulland TK,Jain N,Hornick EE,Elliott EI,Clay GM,Sadler JJ,Mills KA,Janowski AM,Volk AP,Wang K,Legge KL,Gakhar L,Bourdi M,Ferguson PJ,Wilson ME,Cassel SL,Sutterwala FS
14-7061 was used in an ELISA assay to demonstrate that C57BL/6J mice have a functional defect in NLRP12, which is required by macrophages for effective neutrophil recruitment to inflammatory sites.
Tue Oct 25 00:00:00 UTC 2016
γδ T cells promote inflammation and insulin resistance during high fat diet-induced obesity in mice.
Journal of leukocyte biology
Mehta P,Nuotio-Antar AM,Smith CW
14-7061 was used in Flow cytometry/Cell sorting to reveal that isolated γδ T cells directly stimulated RAW264.7 macrophage TNF-α expression but did not stimulate inflammatory mediator expression in 3T3-L1 adipocytes.
Thu Jan 01 00:00:00 UTC 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950)
Biswas A,Bruder D,Wolf SA,Jeron A,Mack M,Heimesaat MM,Dunay IR
14-7061 was used in Flow cytometry/Cell sorting to indicate the critical importance of recruited Ly6C monocytes upon cerebral toxoplasmosis.
Wed Apr 01 00:00:00 UTC 2015
Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation.
PloS one
Pannu J,Belle JI,Förster M,Duerr CU,Shen S,Kane L,Harcourt K,Fritz JH,Clare S,Nijnik A
14-7061 was used in an ELISA assay to indicate that USP21 is redundant for regulation of GATA3 and RIPK1 activity during mouse development, hematopoiesis, and lymphocyte differentiation.
Mon Dec 28 00:00:00 UTC 2015
Sprouty1 induces a senescence-associated secretory phenotype by regulating NFκB activity: implications for tumorigenesis.
Cell death and differentiation
Macià A,Vaquero M,Gou-Fàbregas M,Castelblanco E,Valdivielso JM,Anerillas C,Mauricio D,Matias-Guiu X,Ribera J,Encinas M
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Neutralization
Sat Feb 01 00:00:00 UTC 2014
Persistently active microbial molecules prolong innate immune tolerance in vivo.
PLoS pathogens
Lu M,Varley AW,Munford RS
14-7061-81 was used in Flow Cytometry to demonstrate a novel mechanism for tolerance reprogramming following exposure to Gram-negative bacteria.
Wed May 01 00:00:00 UTC 2013
Immunoproteasome deficiency modifies the alternative pathway of NFκB signaling.
PloS one
Maldonado M,Kapphahn RJ,Terluk MR,Heuss ND,Yuan C,Gregerson DS,Ferrington DA
14-7061 was used in an ELISA assay to investigate whether the classical or alternative pathways are regulated by the immunoproteasome following chronic TNFα exposure.
Mon Aug 26 00:00:00 UTC 2013
Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage.
PloS one
Gahring LC,Enioutina EY,Myers EJ,Spangrude GJ,Efimova OV,Kelley TW,Tvrdik P,Capecchi MR,Rogers SW
14-7061 was used in Flow cytometry/Cell sorting to investigate how inflammatory responses are mechanistically modulated by nicotinic acetylcholine receptors.
Tue Aug 27 00:00:00 UTC 2013
Cytip regulates dendritic-cell function in contact hypersensitivity.
European journal of immunology
Heib V,Sparber F,Tripp CH,Ortner D,Stoitzner P,Heufler C
14-7061 was used in Flow cytometry/Cell sorting to evaluate the functional consequences of cytohesin-interacting protein (Cytip) deficiency in dendritic cells using Cytip knockout mice.
Thu Mar 01 00:00:00 UTC 2012
Deletion of Syk in neutrophils prevents immune complex arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Elliott ER,Van Ziffle JA,Scapini P,Sullivan BM,Locksley RM,Lowell CA
14-7061 was used in Flow cytometry/Cell sorting to investigate the specific cell types in which FcγR signalling through spleen tyrosine kinase is required for arthritis development in the serum transfer model.
Sat Oct 15 00:00:00 UTC 2011
Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding.
International immunology
Ashman RF,Goeken JA,Latz E,Lenert P
14-7061 was used in an ELISA assay to explore the use of oligonucleotide sequences for therapeutic purposes in situations where inflammation is enhanced by TLR9.
Tue Mar 01 00:00:00 UTC 2011
Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.
Journal of immunology (Baltimore, Md. : 1950)
Jørgensen TN,Alfaro J,Enriquez HL,Jiang C,Loo WM,Atencio S,Bupp MR,Mailloux CM,Metzger T,Flannery S,Rozzo SJ,Kotzin BL,Rosemblatt M,Bono MR,Erickson LD
14-7061 was used in an ELISpot assay to identify gene intervals within Nba2 that control the development of autoantibody-producing B cells.
Fri Jan 15 00:00:00 UTC 2010
Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression.
Journal of immunology (Baltimore, Md. : 1950)
Wu C,Rauch U,Korpos E,Song J,Loser K,Crocker PR,Sorokin LM
14-7061 was used in Flow cytometry/Cell sorting to propose a new direct cell-cell interaction-based mechanism regulating the expansion of Tregs during autoimmune and inflammatory processes.
Fri May 15 00:00:00 UTC 2009
IL-6 produced by immune complex-activated follicular dendritic cells promotes germinal center reactions, IgG responses and somatic hypermutation.
International immunology
Wu Y,El Shikh ME,El Sayed RM,Best AM,Szakal AK,Tew JG
Published figure using IL-6 monoclonal antibody (Product # 14-7061-81) in Neutralization
Mon Jun 01 00:00:00 UTC 2009
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
Proceedings of the National Academy of Sciences of the United States of America
He R,Oyoshi MK,Jin H,Geha RS
14-7061 was used in Immunocytochemistry to suggest that in patients with atopic dermatitis, initial cutaneous exposure to antigens may induce the production of IL-17, driving inflammation in the airways.
Tue Oct 02 00:00:00 UTC 2007
