Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
蛋白别名: CDw210b; CRF2-4; cytokine receptor class-II CRF2-4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; cytokine receptor family II, member 4; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10RB; inte; interleukin 10 receptor, beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta
基因别名: CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2; IL10RB; RGD1560373
UniProt ID: (Human) Q08334
分子生物学功能: transmembrane signal receptor