This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for human IL1F10.
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection. IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil. IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses. IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis.
蛋白别名: Family of interleukin 1-theta; FIL1 theta; IL-1 theta; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL-1HY2; IL-38; interleukin 1 family, member 10 (theta); Interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38
基因别名: FIL1-theta; FIL1T; FKSG75; IL-1HY2; IL-38; IL1-theta; IL1F10; IL1HY2; IL38; UNQ6119/PRO20041
UniProt ID: (Human) Q8WWZ1
Entrez Gene ID: (Human) 84639
分子生物学功能: interleukin superfamily