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Proteintech
IL1R2 Monoclonal Antibody (3H4H4)
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产品信息
60262-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
3H4H4
抗原
IL1R2 Fusion Protein Ag4495 (24-347 aa encoded by BC039031)
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: AARSCRFRG RHYKREFRLE GEPVALRCPQ VPYWLWASVS PRINLTWHKN DSARTVPGEE ETRMWAQDGA LWLLPALQED SGTYVCTTRN ASYCDKMSIE LRVFENTDAF LPFISYPQIL TLSTSGVLVC PDLSEFTRDK TDVKIQWYKD SLLLDKDNEK FLSVRGTTHL LVHDVALEDA GYYRCVLTFA HEGQQYNITR SIELRIKKKK EETIPVIISP LKTISASLGS RLTIPCKVFL GTGTPLTTML WWTANDTHIE SAYPGGRVTE GPRQEYSENN ENYIEVPLIF DPVTREDLHM DFKCVVHNTL SFQTLRTTVK EASST (24-347 aa encoded by B C039031)
靶标信息
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 receptor beta chain; IL-1 type II receptor; IL-1R-2; IL-1R-beta; IL-1RT-2; IL-1RT2; ILR2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; type II interleukin-1 receptor, beta
基因别名: CD121b; CDw121b; IL-1R-2; Il-1r2; IL-1RT-2; IL-1RT2; Il1r-2; IL1R2; IL1R2c; IL1RB
UniProt ID: (Human) P27930, (Mouse) P27931
Entrez Gene ID: (Human) 7850, (Mouse) 16178
