应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫细胞化学 (ICC/IF) |
1:50 - 1:200 | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human IL1RN. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
4.11 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2807854 |
Immunogen sequence: MALETICRPS GRKSSKMQAF RIWDVNQKTF YLRNNQLVAG YLQGPNVNLE EKIDVVPIEP HALFLGIHGG KMCLSCVKSG DETRLQLEAV NITDLSENRK QDKRFAFIRS DSGPTTSFES AACPGWFLCT AMEADQPVSL TNMPDEGVMV TKFYFQEDE; Positive Samples: 293T, HeLa, NIH/3T3, HL-60, BT-474, HT-29; Cellular Location: Cytoplasm
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Anakinra; CD121A; D2S1473; ICIL-1RA; IL 1 receptor antagonist; il-1 receptor; il-1r; IL-1RN; IL1 inhibitor; il1 receptor; IL1 receptor antagonist; IL1-RA; IL1R; IL1RN (IL1F3); interleukin-1 receptor; Interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; MGC10430; P80; type II interleukin-1 receptor antagonist
基因别名: DIRA; F630041P17Rik; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IL1RN; IRAP; MVCD4
UniProt ID: (Human) P18510, (Mouse) P25085
Entrez Gene ID: (Human) 3557, (Mouse) 16181
分子生物学功能:
interleukin superfamily