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Invitrogen
IL1RAPL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100574
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IL1RAPL1(Accession Q9NZN1), corresponding to amino acid residues T62-D112.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total IL1RAPL1.
靶标信息
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signaling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytokine receptor; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL; IL1RAPL-1; interleukin 1 receptor-8; Interleukin-1 receptor accessory protein-like 1; Oligophrenin-4; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; X-linked interleukin-1 receptor accessory protein-like 1
基因别名: 6330532G10Rik; C030039N24; IL-1-RAPL-1; IL-1RAPL-1; IL1R8; IL1RAPL; IL1RAPL-1; IL1RAPL1; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2
UniProt ID: (Rat) P59824
Entrez Gene ID: (Human) 11141, (Mouse) 331461, (Rat) 317553
signal transduction
cell surface receptor signaling pathway
regulation of neuron projection development
neuron differentiation
negative regulation of exocytosis
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
presynaptic membrane assembly
regulation of postsynapse organization
trans-synaptic signaling by trans-synaptic complex
synaptic membrane adhesion
regulation of presynapse assembly
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
regulation of ion transmembrane transport
positive regulation of dendrite morphogenesis
calcium ion transmembrane transport
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