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产品信息
PA5-50511
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues near the N terminal of human inhibitor of growth family, member 1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.6 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635964 |
产品详细信息
The antibody detects endogenous levels of total ING1 protein.
靶标信息
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: growth inhibitor ING1; growth inhibitory protein ING1; inhibitor of growth family, member 1; Inhibitor of growth protein 1; p33ING; tumor suppressor ING1
基因别名: 2610028J21Rik; AA407184; AI875420; ING1; mING1h; p24ING1c; p33; p33ING1; p33ING1b; p37Ing1b; p47; p47ING1a
UniProt ID: (Human) Q9UK53, (Mouse) Q9QXV3
Entrez Gene ID: (Human) 3621, (Mouse) 26356
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein
