应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.1-0.5 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide corresponding to a sequence in the middle region of human ING1, different from the related mouse sequence by seven amino acids. |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
500 µg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS with 5mg BSA |
内含物 |
0.05mg sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2807098 |
Synthetic peptide sequence: 192-223aa, KELDECYERFSRETDGAQKRRMLHCVQRALIR.
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: growth inhibitor ING1; growth inhibitory protein ING1; inhibitor of growth family, member 1; Inhibitor of growth protein 1; p33ING; tumor suppressor ING1
基因别名: ING1; p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
UniProt ID: (Human) Q9UK53
Entrez Gene ID: (Human) 3621
分子生物学功能:
chromatin/chromatin-binding, or -regulatory protein