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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
蛋白别名: growth inhibitor ING1; growth inhibitory protein ING1; inhibitor of growth family, member 1; Inhibitor of growth protein 1; p33ING; tumor suppressor ING1
基因别名: ING1; p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
UniProt ID: (Human) Q9UK53
Entrez Gene ID: (Human) 3621