Proteintech

IQGAP3 Polyclonal Antibody

Name: IQGAP3 Polyclonal Antibody
Brand: Proteintech
SKU: 25930-1-AP

6 篇参考文献

查看其他6个IQGAP3抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

IQGAP3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 5

IQGAP3 Antibody (25930-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using 25930-1-AP (IQGAP3 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

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Immunogen image

Immunogen Image IQGAP3 Polyclonal Antibody

产品信息

25930-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

查看4篇已发表文章 4篇已发表文章

免疫组化 (IHC)

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

IQGAP3 Fusion Protein Ag23109 (530-880 aa encoded by BC131536)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: LINEALDKG SPEKTLSALL LPAAGLDDVS LPVAPRYHLL LVAAKRQKAQ VTGDPGAVLW LEEIRQGVVR ANQDTNTAQR MALGVAAINQ AIKEGKAAQT ERVLRNPAVA LRGVVPDCAN GYQRALESAM AKKQCPADTA FWVQHDMKDG TAYYFHLQTF QGIWEQPPGC PLNTSHLTRE EIQSAVTKVT AAYDRQQLWK ANVGFVIQLQ ARLRGFLVRQ KFAEHSHFLR TWLPAVIKIQ AHWRGYRQRK IYLEWLQYFK ANLDAIIKIQ AWARMWAARR QYLRRLHYFQ KNVNSIVKIQ AFFRARKAQD DYRILVHAPH PPLSVVRRFA HLLNQSQQDF LAEAELLKLQ EE (530-880 aa encoded by BC131536)

靶标信息

IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

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