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Abnova
ISG20L1 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00064782-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ISG20L1 (NP_073604.2, 1 a.a. approximately 325 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MVPREAPESA QCLCPSLTIP NAKDVLRKRH KRRSRQHQRF MARKALLQEQ GLLSMPPEPG SSPLPTPFGA ATATEAASSG KQCLRAGSGS APCSRRPAPG KASGPLPSKC VAIDCEMVGT GPRGRVSELA RCSIVSYHGD VLYDKYIRPE MPIADYRTRW SGITRQHMRK AVPFQVAQKE ILKLLKGKVV VGHALHNDFQ ALKYVHPRSQ TRDTTYVPNF LSEPGLHTRA RVSLKDLALQ LLHKKIQVGQ HGHSSVEDAT TAMELYRLVE VQWEQQEARS LWTCPEDREP DSSTDMEQYM EDQYWPDDLA HGSRGGAREA QDRRN
靶标信息
Apoptosis-Enhancing Nuclease (AEN) is a nuclear exonuclease that serves as a critical player in p53-mediated apoptosis. Induced by p53 in response to various DNA damage signals, AEN is involved in the degradation of cellular DNA during apoptosis. The nuclease activity of AEN contributes to the controlled dismantling of cellular components, ensuring that the apoptotic process leads to the efficient and timely removal of damaged or unwanted cells. Its expression regulation via phosphorylation highlights the intricacy of apoptotic signaling pathways and underscores the importance of AEN in maintaining genomic stability and preventing tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apoptosis-enhancing nuclease; Interferon-stimulated 20 kDa exonuclease-like 1
基因别名: AEN; ISG20L1; SBBI58
Entrez Gene ID: (Human) 64782
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
