Invitrogen

ITGA5 Recombinant Superclonal Antibody

高级验证

This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.

查看其他28个CD49e (Integrin alpha 5)抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)
高级验证 (1)

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ITGA5 Antibody (711210) in WB

Western blot analysis was performed on Membrane enriched cell extracts (30 µg lysate) of U-87 MG (Lane 1), A-431 (Lane 2), U-937 (Lane 3), THP-1 (Lane 4), HeLa (Lane 5) and Tissue lysates of Mouse Heart (Lane 6) and Rat Heart (Lane 7). The blots were probed with Anti-Integrin alpha 5 beta 1 Recombinant Rabbit Polyclonal Antibody (Product # 711210, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 160 kDa band ... View More

Product Image Gallery

ITGA5 Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. HeLa cells were transfected with ITGA5I siRNA and loss of signal was observed in Western blot using Anti-ITGA5 Recombinant Rabbit Polyclonal Antibody (Product # 711210). {KD}

产品信息

711210

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Superclonal

类型

Antibody

抗原

Protein corresponding to Human ITGA5 (aa 800-1050)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2633132

产品详细信息

This antibody is predicted to react with Monkey, Horse, Cat and Bovine

Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

靶标信息

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5

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基因别名: CD49e; FNRA; ITGA5; Itga5_retired; VLA-5; VLA5; VLA5A

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UniProt ID: (Human) P08648, (Mouse) P11688

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Entrez Gene ID: (Human) 3678, (Mouse) 16402, (Rat) 315346

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功能

virus receptor activity epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding protein binding vascular endothelial growth factor receptor 2 binding metal ion binding cell adhesion molecule binding receptor activity integrin

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