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Invitrogen
ITLN1/ITLN2 Monoclonal Antibody (450515)
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产品信息
MA5-61409
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
450515
抗原
E.coli-derived recombinant human Intelectin-1, Thr19-Ser298
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
ITLN1 (Intelectin-1) and ITLN2 (Intelectin-2) are genes encoding proteins that belong to the intelectin family, which are involved in immune response and metabolic regulation. Intelectin-1, also known as omentin-1, is primarily expressed in visceral fat and plays a role in enhancing insulin signaling, thus contributing to glucose metabolism and insulin sensitivity. It has anti-inflammatory properties and is associated with protective effects against obesity-related diseases such as type 2 diabetes and cardiovascular diseases. Intelectin-2, while less well-characterized, is believed to share similar functions and may also be involved in pathogen recognition and defense, particularly in the intestines. Both ITLN1 and ITLN2 are implicated in the recognition of microbial carbohydrates, suggesting a role in innate immunity. Alterations in the expression of these genes have been linked to various metabolic and inflammatory conditions. Consequently, ITLN1 and ITLN2 are considered important targets for research into metabolic disorders, inflammation, and immune response, with potential therapeutic implications for treating related diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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