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Recommended positive controls: HeLa, Jurkat, mouse brain, PC-12.
Predicted reactivity: Mouse (90%), Rat (90%), Pig (91%), Chicken (85%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
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蛋白别名: Butyryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; isovaleryl dehydrogenase; Isovaleryl-CoA dehydrogenase, mitochondrial; IVD
基因别名: 1300016K07Rik; 6720455E18Rik; ACAD2; AI463340; IVD
UniProt ID: (Human) P26440, (Rat) P12007, (Mouse) Q9JHI5
Entrez Gene ID: (Human) 3712, (Rat) 24513, (Mouse) 56357
分子生物学功能:
dehydrogenase
