MUbio

Integrin beta 1D Monoclonal Antibody (1G2)

Name: Integrin beta 1D Monoclonal Antibody (1G2)
Brand: MUbio
SKU: MUB0907P

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MUB0907P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:500

免疫组化（冰冻） (IHC (F))

1:50-1:100

免疫细胞化学 (ICC/IF)

Assay-dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

1G2

抗原

Integrin beta 1D

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

1G2 recognizes specifically the cytoplasmic domain of integrin subunit beta-1D present in cardiac and skeletal muscle.

A broad species reactivity is expected because of the conserved nature of the epitope.

The antibody may be stored at 4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.

靶标信息

Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migRation and apoptosis. There are two major forms of integrin beta 1: Beta 1A and Beta 1D, which differ in 13 amino acids. Their distribution pattern in adult tissues is mutually exclusive. Beta 1A is present in all tissues, except cardiac and skeletal muscle, which instead express the Beta 1D variant.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: CD29; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; integrin beta 1; Integrin beta-1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); very late activation protein, beta polypeptide; VLA-4 subunit beta

查看更多收起

基因别名: 4633401G24Rik; AA409975; AA960159; CD29; ENSMUSG00000051907; FNRB; Gm9863; GPIIA; ITGB1; MDF2; MSK12; VLA-BETA; VLAB

查看更多收起

UniProt ID: (Human) P05556, (Mouse) P09055

查看更多收起

Entrez Gene ID: (Human) 3688, (Mouse) 16412

查看更多收起

功能