Leinco Technologies

Integrin beta 7 Monoclonal Antibody (FIB504), Functional Grade, In Vivo PLATINUM™

Name: Integrin beta 7 Monoclonal Antibody (FIB504), Functional Grade, In Vivo PLATINUM\u2122
Brand: Leinco Technologies
SKU: B763-100MG

查看其他25个Integrin beta 7抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

Immunogen image

Immunogen Image Integrin beta 7 Monoclonal Antibody (FIB504), Functional Grade, In Vivo PLATINUM™

产品信息

B763-100MG

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-dependent

免疫沉淀 (IP)

Assay-dependent

功能检测 (Functional)

Assay-dependent

抑制试剂 (IA)

Assay-dependent

Mass Spectrometry (MS)

Assay-dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Rat / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

FIB504

抗原

TK1 cells

查看免疫原

偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Clone FIB504 recognizes an epitope on human/mouse integrin Beta7.

Endotoxin Level: <0.5 EU/mg as determined by the LAL method.

Purity: ≥98% monomer by analytical SEC and >95% by SDS Page.

Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.

Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.

靶标信息

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

仅用于科研。不用于诊断过程。未经明确授权不得转售。