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Proteintech
Intersectin 1 Polyclonal Antibody
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产品信息
21862-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Intersectin 1 Fusion Protein Ag16517 (610-926 aa encoded by BC116186)
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LREIHNKQQ LQKQKSMEAE RLKQKEQERK IIELEKQKEE AQRRAQERDK QWLEHVQQED EHQRPRKLHE EEKLKREESV KKKDGEEKGK QEAQDKLGRL FHQHQEPAKP AVQAPWSTAE KGPLTISAQE NVKVVYYRAL YPFESRSHDE ITIQPGDIVM VKGEWVDESQ TGEPGWLGGE LKGKTGWFPA NYAEKIPENE VPAPVKPVTD STSAPAPKLA LRETPAPLAV TSSEPSTTPN NWADFSSTWP TSTNEKPETD NWDAWAAQPS LTVPSAGQLR QRSAFTPATA TGSSPSPVLG QGEKVEGLQA QALYPWRA (610-926 aa encoded by BC116186)
靶标信息
The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: human intersectin-SH3 domain-containing protein SH3P17; intersectin 1 (SH3 domain protein); Intersectin-1; MGC134948; MGC134949; SH3 domain-containing protein 1A; SH3P17; Src homology 3 domain-containing protein; subject to NMD; unnamed protein product
基因别名: ITSN; ITSN1; SH3D1A; SH3P17
UniProt ID: (Human) Q15811
Entrez Gene ID: (Human) 6453
exocytosis
endocytosis
protein localization
regulation of cell communication
protein transport
endosomal transport
regulation of signaling
intracellular signal transduction
regulation of small GTPase mediated signal transduction
positive regulation of growth hormone secretion
positive regulation of dendritic spine development
regulation of postsynapse organization
clathrin-dependent synaptic vesicle endocytosis
regulation of modification of postsynaptic actin cytoskeleton
positive regulation of caveolin-mediated endocytosis
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