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Invitrogen
Iscalimab Humanized Recombinant Human Monoclonal Antibody
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产品信息
MA5-42187
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human CD40/TNFRSF5
偶联物
形式
Liquid
浓度
1.24 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.5
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Iscalimab (CFZ533) is a new, fully humanized monoclonal antibody that targets cluster of differentiation 40 (CD40), which can regulate the CD40-CD154 costimulatory pathway and prevent CD40 pathway signal transduction and CD40+ cell type activation. It is expected Become a new treatment for solid organs and related autoimmune diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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