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Invitrogen
JAM-A (CD321) Polyclonal Antibody
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产品信息
PA1-4226
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues V(1) N L K S S N(7) C H(304) K S S F V I(310) of the N- and C-termini of mouse JAM-2.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-4226 detects the Junctional Adhesion Molecule (JAM-2) in mouse samples.
PA1-4226 has been successfully used in Western blot procedures.
PA1-4226 immunogen is a synthetic peptide corresponding to residues V(1) N L K S S N(7) C H(304) K S S F V I(310) of the N- and C-termini of mouse JAM-2, separated by a cysteine.
靶标信息
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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