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Invitrogen
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Immunogen sequence: LGSQSTNSSYT MNTKTGTLQF NTVSKLDTGE Y
Highest antigen sequence identity to the following orthologs - mouse 66%, rat 69%.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。