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Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:10,000 | 查看2篇已发表文章 2篇已发表文章 |
免疫组化（石蜡） (IHC (P)) |
1:100 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
染色质免疫沉淀 实验 (ChIP) |
Assay-Dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
已发表种属 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide made to an internal region of the human JMJD2C protein (within residues 450-600). |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.0 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS |
内含物 |
0.05% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11152049 |
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: [histone H3]-trimethyl-L-lysine(9) demethylase 4C; bA146B14.1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; Gene amplified in squamous cell carcinoma 1 protein; JmjC domain-containing histone demethylation protein 3C; jumonji domain containing 2C; Jumonji domain-containing protein 2C; lysine (K)-specific demethylase 4C; Lysine-specific demethylase 4C; RP11-169L18.1; tudor domain containing 14C
基因别名: 2410141F18Rik; AA517467; GASC1; JHDM3C; JMJD2C; KDM4C; KIAA0780; TDRD14C
UniProt ID: (Human) Q9H3R0, (Mouse) Q8VCD7
Entrez Gene ID: (Human) 23081, (Mouse) 76804
分子生物学功能:
histone modifying enzyme
