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Proteintech
JMJD6 Polyclonal Antibody
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产品信息
16476-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
JMJD6 Fusion Protein Ag9590 (1-403 aa encoded by BC066654)
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MNHKSKKRI REAKRSARPE LKDSLDWTRH NYYESFSLSP AAVADNVERA DALQLSVEEF VERYERPYKP VVLLNAQEGW SAQEKWTLER LKRKYRNQKF KCGEDNDGYS VKMKMKYYIE YMESTRDDSP LYIFDSSYGE HPKRRKLLED YKVPKFFTDD LFQYAGEKRR PPYRWFVMGP PRSGTGIHID PLGTSAWNAL VQGHKRWCLF PTSTPRELIK VTRDEGGNQQ DEAITWFNVI YPRTQLPTWP PEFKPLEILQ KPGETVFVPG GWWHVVLNLD TTIAITQNFA SSTNFPVVWH KTVRGRPKLS RKWYRILKQE HPELAVLADS VDLQESTGIA SDSSSDSSSS SSSSSSDSDS ECESGSEGDG TVHRRKKRRT CSMVGNGDTT SQDDCVSKER SSSR (1-403 aa encoded by BC066654)
靶标信息
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: apoptotic cell clearance receptor PtdSerR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; jumonji domain containing 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR
基因别名: 5730436I23Rik; D11Ertd195e; JMJD6; KIAA0585; mKIAA0585; PSR; PtdSerR; PTDSR; PTDSR1
UniProt ID: (Human) Q6NYC1, (Mouse) Q9ERI5, (Rat) Q6AYK2
Entrez Gene ID: (Human) 23210, (Mouse) 107817, (Rat) 360665
RNA binding
single-stranded RNA binding
receptor activity
iron ion binding
protein binding
histone demethylase activity
histone demethylase activity (H3-R2 specific)
histone demethylase activity (H4-R3 specific)
identical protein binding
protein homodimerization activity
peptidyl-lysine 5-dioxygenase activity
sulfonate dioxygenase activity
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
molecular_function
protein modifying enzyme
kidney development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cell surface receptor signaling pathway
heart development
RNA splicing
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
lung development
T cell differentiation in thymus
macrophage activation
recognition of apoptotic cell
regulation of mRNA splicing, via spliceosome
erythrocyte development
oxidation-reduction process
retina development in camera-type eye
histone H3-R2 demethylation
histone H4-R3 demethylation
blood vessel development
multicellular organism development
chromatin modification
cell differentiation
apoptotic cell clearance
biological_process
