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Proteintech
JNK2 Polyclonal Antibody
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产品信息
51153-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Rabbit
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
JNK2 Fusion Protein Ag1442 (1-424 aa encoded by BC032539)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSDSKCDSQ FYSVQVADST FTVLKRYQQL KPIGSGAQGI VCAAFDTVLG INVAVKKLSR PFQNQTHAKR AYRELVLLKC VNHKNIISLL NVFTPQKTLE EFQDVYLVME LMDANLCQVI HMELDHERMS YLLYQMLCGI KHLHSAGIIH RDLKPSNIVV KSDCTLKILD FGLARTACTN FMMTPYVVTR YYRAPEVILG MGYKENVDIW SVGCIMGELV KGCVIFQGTD HIDQWNKVIE QLGTPSAEFM KKLQPTVRNY VENRPKYPGI KFEELFPDWI FPSESERDKI KTSQARDLLS KMLVIDPDKR ISVDEALRHP YITVWYDPAE AEAPPPQIYD AQLEEREHAI EEWKELIYKE VMDWEERSKN GVVKDQPSDA AVSSNATPSQ SSSINDISSM STEQTLASDT DSSLDASTGP LEGCR (1-424 aa encoded by BC032539)
靶标信息
MAPK9 (JNK2) is a serine/threonine kinase which plays an important role in the MAPK pathway. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK; JNK-46; JNK-55; JNK/SAPK alpha; JNK1; JNK1A2; JNK21B1/2; Jun kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54-alpha; PRKM8; protein kinase, mitogen-activated 9; SAPK-alpha; SAPK1; SAPK1a; SAPK1c; stress activated protein kinase alpha II; Stress-activated protein kinase 1a; Stress-activated protein kinase JNK2
基因别名: AI851083; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1A
UniProt ID: (Human) Q15711, (Rat) P49186, (Mouse) Q9WTU6
Entrez Gene ID: (Human) 5601, (Rat) 50658, (Mouse) 26420
JUN kinase activity
protein binding
ATP binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
mitogen-activated protein kinase kinase kinase binding
MAP kinase activity
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
release of cytochrome c from mitochondria
positive regulation of protein phosphorylation
protein phosphorylation
protein targeting to mitochondrion
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to stress
JNK cascade
JUN phosphorylation
central nervous system development
response to mechanical stimulus
response to toxic substance
positive regulation of gene expression
positive regulation of macrophage derived foam cell differentiation
positive regulation of cell morphogenesis involved in differentiation
response to amine
neuron projection development
positive regulation of prostaglandin biosynthetic process
regulation of protein ubiquitination
positive regulation of prostaglandin secretion
positive regulation of chemokine production
cellular response to UV
Fc-epsilon receptor signaling pathway
response to drug
regulation of circadian rhythm
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
regulation of JNK cascade
response to cadmium ion
rhythmic process
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of podosome assembly
positive regulation of apoptotic signaling pathway
MAPK cascade
response to organic substance
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
phosphorylation
