Invitrogen

Jagged1 Polyclonal Antibody

Jagged1 Antibody in Immunocytochemistry (ICC/IF)

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Jagged1 Antibody (PA5-86057) in ICC/IF

Immunocytochemical analysis of Jagged1 in HepG2 cells using a Jagged1 Polyclonal antibody (Product # PA5-86057) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Jagged1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Jagged1 Antibody in Flow Cytometry (Flow)

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产品信息

PA5-86057

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:50-1:200

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide within Human Jagged 1 aa 90-144

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 50% Glycerol, 0.2% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2802858

靶标信息

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.

Communications biology

Cheng L,Xie M,Qiao W,Song Y,Zhang Y,Geng Y,Xu W,Wang L,Wang Z,Huang K,Dong N,Sun Y

PA5-86057 was used in Flow Cytometry to show that hPSC-derived valvular cells could be efficiently generated from hPSCs, which might be used as seed cells for construction of valve organoids or next generation tissue engineered heart valves.