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Invitrogen
JunB Recombinant Rabbit Monoclonal Antibody (15H19L4)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
JunB Antibody (701702) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized HeLa cells for detection of JUNB using Anti-JUNB Recombinant Rabbit Monoclonal Antibody (Product # 701702, 1-2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of JUNB protein (green), Panel b) is stained for nuclei (blue) using SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). Panel c) r... View More
产品信息
701702
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
15H19L4
抗原
Peptides corresponding to Human JUNB (aa 6-25, 262-279)
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2609325
产品详细信息
This antibody is predicted to react with Monkey, Rat, Mouse and Feline.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activator protein 1; Jun B; jun B proto-oncogene; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; Transcription factor JunB
基因别名: AP-1; JUNB
UniProt ID: (Human) P17275
Entrez Gene ID: (Human) 3726
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
osteoblast differentiation
trophectodermal cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to light stimulus
response to mechanical stimulus
regulation of cell death
osteoclast differentiation
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
osteoblast proliferation
response to cytokine
regulation of cell proliferation
response to drug
response to peptide hormone
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
decidualization
response to corticosterone
response to cAMP
regulation of cell cycle
embryonic process involved in female pregnancy
labyrinthine layer blood vessel development
cellular response to calcium ion
