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Invitrogen
K-Ras Polyclonal Antibody
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产品信息
PA5-27234
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 73 of Human K-Ras
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA5-27234 targets K-Ras in IF, IHC (P), ELISA, IP and WB applications and shows reactivity with Human samples.
The PA5-27234 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 73 of Human K-Ras.
靶标信息
K-RAS (GTPase KRas) belongs to the Ras oncogene family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. It plays an important role in the regulation of cell proliferation and has a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells in a ZNF304-dependent manner. Mutations in the gene can result in leukemia acute myelogenous, leukemia juvenile myelomonocytic, Noonan Syndrome, gastric cancer, and cardiofaciocutaneous syndrome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
